Protein Alignment Bace and asp-4

DIOPT Version :9

• Sequence 1: NP_001285756.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_510191.1
• Gene: asp-4 / 181444
• WormBaseID: WBGene00000217
• Length: 444
• Species: Caenorhabditis elegans
• Alignment Length: 394
• Identity: 180/394 - (45%)
• Similarity: 235/394 - (59%)
• Gaps: 48/394 - (12%)

  Fly    14 LASAELHRVPILKE--------QNFVKTRQNVLAEKSYLRT-------KYQLPSLRSVDEEQLSN 63
            |.:..|.:.|.|:|        :.|.|.|...   |.||:|       |||..::....:|.|.|
 Worm    27 LRTVSLKKQPTLRETLLQAGSFETFAKHRHGY---KKYLKTNGNHHFDKYQALNVEGEIDELLRN 88

  Fly    64 SMNMAYYGAISIGTPAQSFKVLFDSGSSNLWVPSNTCK--SDACLTHNQYDSSASSTYVANGESF 126
            .|:..|:|.||||||||:|.|:||:||||||:||..|.  ..||:.|::|||.:||||..:|...
 Worm    89 YMDAQYFGTISIGTPAQNFTVIFDTGSSNLWIPSKKCPFYDIACMLHHRYDSKSSSTYKEDGRKM 153

  Fly   127 SIQYGTGSLTGYLSTDTVDVNGLSIQSQTFAESTNEPGTNFNDANFDGILGMAYESLAVDGVAPP 191
            :|||||||:.|::|.|:|.|.|:..:.|.|||:|:|||..|..|.|||||||||..:||.||.|.
 Worm   154 AIQYGTGSMKGFISKDSVCVAGVCAEDQPFAEATSEPGITFVAAKFDGILGMAYPEIAVLGVQPV 218

  Fly   192 FYNMVSQGLVDNSVFSFYLARDGTSTMGGELIFGGSDASLYSGALTYVPISEQGYWQFTM---AG 253
            |..:..|..|.:::|||:|.|:..|.:|||:.|||.|:..|...:||||::.:|||||.|   .|
 Worm   219 FNTLFEQKKVPSNLFSFWLNRNPDSEIGGEITFGGIDSRRYVEPITYVPVTRKGYWQFKMDKVVG 283

  Fly   254 SSIDGYSLCDDCQAIADTGTSLIVAPYNAYITL------SEILNVGEDGY-LDCSSVSSLPDVTF 311
            |.:.|.|  :.||||||||||||..| .|.|..      :|.|..||  | :.|..|.:||.|:|
 Worm   284 SGVLGCS--NGCQAIADTGTSLIAGP-KAQIEAIQNFIGAEPLIKGE--YMISCDKVPTLPPVSF 343

  Fly   312 NIGGTNFVLKPSAYIIQ-SDGN---CMSAFEYMGTD-------FWILGDVFIGQYYTEFDLGNNR 365
            .|||..|.||...|::: |.|.   |:|.|  ||.|       .|||||||||:||:.||...||
 Worm   344 VIGGQEFSLKGEDYVLKVSQGGKTICLSGF--MGIDLPERVGELWILGDVFIGRYYSVFDFDQNR 406

  Fly   366 IGFA 369
            :|||
 Worm   407 VGFA 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bace	NP_001285756.1	pepsin_retropepsin_like	59..369	CDD:299705	163/332 (49%)
		Asp	68..371	CDD:278455	161/325 (50%)
asp-4	NP_510191.1	pepsin_retropepsin_like	88..411	CDD:386101	163/330 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.890