Protein Alignment Bace and asp-12

DIOPT Version :9

• Sequence 1: NP_001285756.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_505134.1
• Gene: asp-12 / 179210
• WormBaseID: WBGene00017678
• Length: 395
• Species: Caenorhabditis elegans
• Alignment Length: 396
• Identity: 131/396 - (33%)
• Similarity: 204/396 - (51%)
• Gaps: 36/396 - (9%)

  Fly     1 MFKTIAVVVLLAALASAEL--HRVPILKEQNFVKTRQNVLAEKSYLRTKYQL----PSLRSVDEE 59
            |..|:...|.:..:.||.:  |::...:.......|:....  :|::.|..|    |::.:...:
 Worm     1 MKTTLLAFVAILGMCSATVVQHKLIYRESPKMQMMRRGEWG--AYVQHKAALRDANPAVFASAPQ 63

  Fly    60 QLSNSMNMAYYGAISIGTPAQSFKVLFDSGSSNLWVPSNTCKSDACLTHNQYDSSASSTYVANGE 124
            .:::..::.|.|.|:||||.|.|.|:.|:||:|||||.:.| ...|...:::|||.|:|:..||:
 Worm    64 NVNDFGDVEYLGNITIGTPPQQFIVVLDTGSANLWVPGSNC-DGTCKGKSEFDSSKSTTFKKNGQ 127

  Fly   125 SFSIQYGTGSLTGYLSTDTVDVNGLS-----IQSQTFAESTNEPGTNFNDANFDGILGMAYESLA 184
            |:.|||.:||..|.:..|||...|.|     :.|.||..::: ..:||.:...:||||:|:.|||
 Worm   128 SWQIQYESGSAKGIMGVDTVAFGGASEQQLLVPSTTFGIASH-ISSNFKNDAAEGILGLAFTSLA 191

  Fly   185 VDGVAPPFYNMVSQGLVDNSVFSFYLARDGT--STMGGELIFGGSDASLYSGALTYVPISEQGYW 247
            ||||.||..|.:::.::|..:|:.:|...||  :..||...:|..|.:.....:.|.|:|...|:
 Worm   192 VDGVTPPLINAINKKILDQPLFTVFLEHKGTAKNVGGGVFTYGAVDTTNCGPVIAYQPLSSATYY 256

  Fly   248 QFTMAGSSIDGYSLCDDCQAIADTGTSLIVAPYNAYITLSEILNV----GEDG-YLDCSSVSSLP 307
            ||...|..:..||.....|.|:|||:|||..|.......::.|..    .:|. ||.||:.....
 Worm   257 QFVADGFKLGSYSNNKKSQVISDTGSSLIGGPSAVINGFAQALGAKYHSDDDAYYLPCSTSKGTL 321

  Fly   308 DVTFNIGGTNFVLKPSAYII---QSDGNCMSAFEYMGTDF------WILGDVFIGQYYTEFDLGN 363
            |:|  |||..:.::|..||:   ..|....:||.:   ||      ||.||.||.||...:|:|.
 Worm   322 DIT--IGGNVYSIEPVNYILDVGMGDTCVFAAFSF---DFGGFGPSWIFGDPFIRQYCNIYDIGQ 381

  Fly   364 NRIGFA 369
            .|||||
 Worm   382 QRIGFA 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bace	NP_001285756.1	pepsin_retropepsin_like	59..369	CDD:299705	118/330 (36%)
		Asp	68..371	CDD:278455	120/323 (37%)
asp-12	NP_505134.1	Asp	72..388	CDD:365818	120/323 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161966
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.850