Protein Alignment Bace and asp-8

DIOPT Version :9

• Sequence 1: NP_001285756.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_503825.2
• Gene: asp-8 / 178750
• WormBaseID: WBGene00019105
• Length: 386
• Species: Caenorhabditis elegans
• Alignment Length: 395
• Identity: 122/395 - (30%)
• Similarity: 190/395 - (48%)
• Gaps: 41/395 - (10%)

  Fly     1 MFKTIAVVVLLAALASAELHRVPILKEQNFVKTRQNVLAEKSYLRTKYQLPSLRSVDEEQLSNSM 65
            ||..:..::.|.||.||....:.:.|..:.   |:.::.|..|.:...::..| |.......:..
 Worm     1 MFGKLISLLGLVALCSAGQFSISVEKSGSL---REQLIREGRYGQELARIQQL-STGNVSFFDHF 61

  Fly    66 NMAYYGAISIGTPAQSFKVLFDSGSSNLWVPSNTCKSDACLTH-------NQYDSSASSTYVANG 123
            :..|...:.||||||.|:|.||:.||||||....|:|..|  |       .:|:.:||||:||..
 Worm    62 DEYYTAGVRIGTPAQHFQVAFDTTSSNLWVFGVECRSQNC--HGGRGRRDREYNRTASSTFVAGT 124

  Fly   124 ESFSIQYGTGSLTGYLSTDTVDVNGLSIQSQTFAESTNEPGTNFNDANFDGILGMAYESLAVDGV 188
            .||::.|..|.::|.:..||....|.:||||.|...|  ..|......|||:||:.:.:.|::|.
 Worm   125 SSFNLPYDGGHVSGNVGKDTAQFAGFTIQSQDFGIGT--AATRLFGETFDGVLGLGWPATALNGT 187

  Fly   189 APPFYNMVSQGLVDNSVFSFYLARDG--TSTMGGELIFGGSDASLYSGALTYVPISEQGYWQFTM 251
            :....|::.|  :|..:|:.|..:..  ..|.||:::||..|.:.....:.|||::...:|.:::
 Worm   188 STTMQNLLPQ--LDQKLFTTYFTKSNMHNGTAGGDIMFGAIDTTHCQSQVNYVPLAYNSFWSYSV 250

  Fly   252 AGSSIDGYSLCDDCQAIADTGTSLIVAPYNAYITLSEILNVGEDGY--------LDCSSVSSLPD 308
            .|.||..||.......|.||.:.....|   .:.|:.|:......|        |.|||.::|||
 Worm   251 DGFSIGTYSRTQTETTIPDTSSGWTGVP---NVVLAGIVKATGATYDWNHQAYTLPCSSTATLPD 312

  Fly   309 VTFNIGGTNFVLKPSAYIIQ---SDGNCMSAFEYMGT------DFWILGDVFIGQYYTEFDLGNN 364
            :.|.|||.::.::...|::.   .:|.|  |....||      ..|||||.|:..|...||.||:
 Worm   313 MVFTIGGNSYNVRAVEYVVNLNLPNGQC--ALSLFGTAASQSGPAWILGDNFLRSYCHVFDFGNS 375

  Fly   365 RIGFA 369
            |||.|
 Worm   376 RIGLA 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bace	NP_001285756.1	pepsin_retropepsin_like	59..369	CDD:299705	108/335 (32%)
		Asp	68..371	CDD:278455	109/328 (33%)
asp-8	NP_503825.2	pepsin_like	65..381	CDD:133138	109/327 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161978
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.750