Protein Alignment IDH2 and Idh2

DIOPT Version :10

• Sequence 1: NP_002159.2
• Gene: IDH2 / 3418
• HGNCID: 5383
• Length: 452
• Species: Homo sapiens
• Sequence 2: NP_001014183.1
• Gene: Idh2 / 361596
• RGDID: 1597139
• Length: 452
• Species: Rattus norvegicus
• Alignment Length: 452
• Identity: 428/452 - (94%)
• Similarity: 438/452 - (96%)
• Gaps: 0/452 - (0%)

Human     1 MAGYLRVVRSLCRASGSRPAWAPAALTAPTSQEQPRRHYADKRIKVAKPVVEMDGDEMTRIIWQF 65
            ||||||.|.||||||||...||||||..|:..||||||||:|||||.||||||||||||||||||
  Rat     1 MAGYLRAVSSLCRASGSTRTWAPAALNVPSWPEQPRRHYAEKRIKVEKPVVEMDGDEMTRIIWQF 65

Human    66 IKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKK 130
            |||||||||||:|||||||||||||||:|||||||||||||||||||||||||||||||||||||
  Rat    66 IKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKK 130

Human   131 MWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMV 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||.||||.||:|
  Rat   131 MWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVVDRAGMFKLV 195

Human   196 FTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDG 260
            ||||||||.||||||||||||||||||||||||||||||||||:||||||||:||||||:|||||
  Rat   196 FTPKDGSGAKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYSIQKKWPLYLSTKNTIMKAYDG 260

Human   261 RFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFG 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   261 RFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFG 325

Human   326 SLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQD 390
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   326 SLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQD 390

Human   391 LIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGRQ 452
            ||||||.||||||:||||||||||||||||||||||||||||||||||||||||||||||:|
  Rat   391 LIRFAQTLEKVCVQTVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGKQ 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IDH2	NP_002159.2	PTZ00435	39..451	CDD:240417	398/411 (97%)
Idh2	NP_001014183.1	PTZ00435	39..451	CDD:240417	398/411 (97%)