Protein Alignment IDH2 and Idh2

DIOPT Version :10

• Sequence 1: NP_002159.2
• Gene: IDH2 / 3418
• HGNCID: 5383
• Length: 452
• Species: Homo sapiens
• Sequence 2: NP_766599.2
• Gene: Idh2 / 269951
• MGIID: 96414
• Length: 452
• Species: Mus musculus
• Alignment Length: 452
• Identity: 430/452 - (95%)
• Similarity: 439/452 - (97%)
• Gaps: 0/452 - (0%)

Human     1 MAGYLRVVRSLCRASGSRPAWAPAALTAPTSQEQPRRHYADKRIKVAKPVVEMDGDEMTRIIWQF 65
            ||||||.|.||||||||...|||||||.|:..||||||||:|||||.||||||||||||||||||
Mouse     1 MAGYLRAVSSLCRASGSARTWAPAALTVPSWPEQPRRHYAEKRIKVEKPVVEMDGDEMTRIIWQF 65

Human    66 IKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKK 130
            |||||||||||:|||||||||||||||:|||||||||||||||||||||||||||||||||||||
Mouse    66 IKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKK 130

Human   131 MWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMV 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||.|||||||:|
Mouse   131 MWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVVDRAGTFKLV 195

Human   196 FTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDG 260
            |||||||..||||||||||||||||||||||||||||||||||:||||||||:||||||||||||
Mouse   196 FTPKDGSSAKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYSIQKKWPLYLSTKNTILKAYDG 260

Human   261 RFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFG 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   261 RFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFG 325

Human   326 SLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQD 390
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   326 SLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQD 390

Human   391 LIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGRQ 452
            ||||||.||||||:||||||||||||||||||||||||||||||||||||||||||||||:|
Mouse   391 LIRFAQTLEKVCVQTVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGKQ 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IDH2	NP_002159.2	PTZ00435	39..451	CDD:240417	399/411 (97%)
Idh2	NP_766599.2	PTZ00435	39..451	CDD:240417	399/411 (97%)