Protein Alignment OR6S1 and srx-62

DIOPT Version :9

• Sequence 1: NP_001001968.1
• Gene: OR6S1 / 341799
• HGNCID: 15363
• Length: 331
• Species: Homo sapiens
• Sequence 2: NP_504114.1
• Gene: srx-62 / 187212
• WormBaseID: WBGene00005953
• Length: 300
• Species: Caenorhabditis elegans
• Alignment Length: 297
• Identity: 58/297 - (19%)
• Similarity: 106/297 - (35%)
• Gaps: 73/297 - (24%)

Human    41 LTGNVLIVGVVRADTRLQTPMYFFLGNLSCLEILLTSVIIPKMLSNFLSRQHTISFAACITQFYF 105
            |:.|..:|..:.:.|.|   :||      |..:||.:.|:.:|       .|...|...:.
 Worm    46 LSANQALVDGLHSTTFL---LYF------CPMVLLDNAIMKEM-------SHHCGFVLLLC---- 90

Human   106 YFFLGASEFLLLAVMSADRYLAICHPLRYPLLMSGAVCFRVALACWVGGLVPVLGPTVAVALLPF 170
               ...|..:.||: |.:|:.|:..|.:|..:.:......:.:..|:.        |.:||:..:
 Worm    91 ---YELSVMIHLAI-SLNRFCAVWIPYQYHNIFNEKNSKILIILIWLF--------TGSVAIYLY 143

Human   171 CKQGAVVQH-FFCDSGPLLRLACTNTKKLEET----DFVLASLVIVSSLLITAVSYGLIVLAV-- 228
                .::.| ::.|....|..  |::|.....    |||..:.::...:||..    |.|:.|
 Worm   144 ----EILCHIYYEDKSDFLTF--TDSKLCANIGWYGDFVKNACIVAVIMLIDI----LTVIKVRR 198

Human   229 ----LSIPSASGRQKAFSTCTSHLIVVTLFYGSAIFL-----YVRPSQSGSVDTNWAVTVITTF- 283
                :|:......|...|:.....:..|:..||...|     :..|..   ....|.|...|:|
 Worm   199 MSRKISVNITEQAQNKLSSREMRFLKQTVTQGSVFLLELLTYFFIPQY---FSNKWIVFFGTSFA 260

Human   284 ----------VTPLLNPFIYA-LRNEQVKEALKDMFR 309
                      |..:.||.:.. |..::.|:.:..|.|
 Worm   261 WVAVHAVDGLVVVIFNPEVRKFLLCKETKKRVSSMNR 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OR6S1	NP_001001968.1	7tm_4	33..308	CDD:304433	56/294 (19%)
		7tm_1	43..293	CDD:278431	53/276 (19%)
srx-62	NP_504114.1	7TM_GPCR_Srx	17..276	CDD:370981	52/274 (19%)
		TM helix 2	43..69	CDD:341315	8/31 (26%)
		TM helix 3	80..110	CDD:341315	8/37 (22%)
		TM helix 4	123..141	CDD:341315	4/25 (16%)
		TM helix 5	167..191	CDD:341315	5/27 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910