DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment d and XIC

DIOPT Version :9

Sequence 1:	NP_001188730.1	Gene:	d / 34179	FlyBaseID:	FBgn0262029	Length:	1426	Species:	Drosophila melanogaster
Sequence 2:	NP_172349.2	Gene:	XIC / 837394	AraportID:	AT1G08730	Length:	1538	Species:	Arabidopsis thaliana

Alignment Length:	802	Identity:	221/802 - (27%)
Similarity:	349/802 - (43%)	Gaps:	156/802 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   472 PKDMQ-------DLIHLSGPLTEHAVMRTLQARFNERRYFTNVGPILLSINPYLDV--------- 520
            |||::       |:..|| .|.|..|::.|:.|:.....:|..|.||::|||:..:
plant    62 PKDVEAPAGGVDDMTKLS-YLHEPGVLQNLKIRYELNEIYTYTGNILIAINPFQRLPHIYDAHMM 125

  Fly   521 ----GNPLTLTSTRAMPLAPQLQKIVQEAVRQQSETGYPQAIILSGTSGAGKTANAMLMLRQLFA 581
                |.||.       .|:|.:..:...|.|.....|...:|::||.||||||....:::|.| |
plant   126 QQYKGAPLG-------ELSPHVFAVADVAYRAMINEGKSNSILVSGESGAGKTETTKMLMRYL-A 182

  Fly   582 IAGGGPETD---AFKHLAAAFTVLRSLGSAKTTTNSESSRIGQFIEVQV-TDGALYRTKIHCYFL 642
            ..||...|:   ..:.:..:..||.:.|:|||..|:.|||.|:|:|:|. ..|.:....|..|.|
plant   183 YLGGRAVTEGRTVEQQVLESNPVLEAFGNAKTVRNNNSSRFGKFVEIQFDKQGRISGAAIRTYLL 247

  Fly   643 DQTRVIRPLPKEKNYHIFYQLLAGLSREERQKLHLDGYSPANLRYLRGDIGQNEQE--------D 699
            :::||.:....|:|||.|| ||....:||.:|..| |: |....||      |:.:        |
plant   248 ERSRVCQISDPERNYHCFY-LLCAAPQEEIEKYKL-GH-PKTFHYL------NQSKCFELVGISD 303

  Fly   700 AARFQAWKTCLGILGIPFLD---VVRVLAAVLLLGNVQFIDG----GGLEVDVKGETELNSVASL 757
            |..:.|.:..:.|:||...:   :.||:||:|.:||:.|..|    ..:..|.|.:..|.:.|.|
plant   304 AHDYLATRRAMDIVGISEKEQEAIFRVVAAILHIGNIDFTKGKEVDSSVPKDEKSKFHLKTAAEL 368

  Fly   758 LGVPPAALFRGLTTRTHNVRGQLVKSVCGDGDANMTRDCLAKALYCRTVATIVRRANSLKRLGST 822
            |.....||...|..|......:::|.......|..:||.|||.:|.|....:|.:.
plant   369 LMCDLKALEDALCKRVMITPEEVIKRSLDPQSAVTSRDGLAKTVYSRLFDWLVDKI--------- 424

  Fly   823 LGTLSSDSNESVHNQADVASQHASTIGGGNAGSKSMAALNNAVRHATSDGFIGILDMFGFEEPSP 887
                    |:|:               |.:|.|:|:               ||:||::|||....
plant   425 --------NKSI---------------GQDANSRSL---------------IGVLDIYGFESFKT 451

  Fly   888 HAHLEHLCINLCAETMQHFYNTHIFKSSVESCRDEGIVCD-TEVDYVDNVPCIDLISSLRTGLLS 951
            :: .|..|||...|.:|..:|.|:||...|....|.|  | :.:::|||...:|||.....|:::
plant   452 NS-FEQFCINFTNEKLQQHFNQHVFKMEQEEYTKEAI--DWSYIEFVDNQDVLDLIEKKPGGIVA 513

  Fly   952 MLDAECSV-RGTAESYVTKLKVQHRSSTRLETKPTAEPHDPRMFLIRHFAGRVEYDTTDFLDTNR 1015
            :||..|.. :.|.|::..||....::..|. .||.....|   |.:.|:||.|.|.:..|||.|:
plant   514 LLDEACMFPKSTHETFANKLYQTFKTHKRF-IKPKLSRTD---FAVAHYAGEVLYQSELFLDKNK 574

  Fly  1016 D-VVPD--DLVGVFYKHTCNFGFATHLFGSELKALYAQQQAPRGLSFRISPTSHSDLLNGDEPVS 1077
            | |:|:  ||:|.   ..|  .|...||..      ..::..:...|                 |
plant   575 DYVIPEHQDLLGA---SKC--PFVVGLFPP------LPEETSKSSKF-----------------S 611

  Fly  1078 TLTQDFHTRLDNLLRTLVHARPHFVRCIRSNGTEAARSFDRATVVRQIRSLQVLETVNLMASGFP 1142
            ::...|..:|..|:.||....||::||::.|.......|:...:::|:|...|||.:.:..:|:|
plant   612 SIGSRFKLQLQQLMETLNCTEPHYIRCVKPNNLLKPAIFENVNIMQQLRCGGVLEAIRISCAGYP 676

  Fly  1143 HRMRFKQFNARYRMLAPFRLLRRSEDKALEDCQLILKYAMEQPPVLDGSVTLAWAPGKRHVFLSE 1207
            .|..|.:|..|:.:|:|..|....::|..  ||          .:||......:..||..|||..
plant   677 TRKPFFEFINRFGLLSPAALEGNFDEKVA--CQ----------KILDNMGLKGYQIGKTKVFLRA 729

  Fly  1208 GIRQHLEHLRTEIRHKSATLMQ 1229
            |....|:..|.|:...:|..:|
plant   730 GQMAELDARRAEVLSSAAKKIQ 751

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
d	NP_001188730.1	MYSc	476..1217	CDD:214580	214/784 (27%)
d	NP_001188730.1	MYSc_Myo20	488..1206	CDD:276847	206/754 (27%)
XIC	NP_172349.2	Myosin_N	19..56	CDD:280832
		MYSc	71..739	CDD:214580	214/779 (27%)
		MYSc_Myo11	84..728	CDD:276835	206/754 (27%)
		Rabaptin	726..>1055	CDD:281520	8/26 (31%)
		MyosinXI_CBD	1119..1504	CDD:271259
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0160
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D311886at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820