DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment d and XIJ

DIOPT Version :9

Sequence 1:	NP_001188730.1	Gene:	d / 34179	FlyBaseID:	FBgn0262029	Length:	1426	Species:	Drosophila melanogaster
Sequence 2:	NP_001319790.1	Gene:	XIJ / 824985	AraportID:	AT3G58160	Length:	1242	Species:	Arabidopsis thaliana

Alignment Length:	898	Identity:	235/898 - (26%)
Similarity:	364/898 - (40%)	Gaps:	218/898 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   472 PKD-------MQDLIHLSGPLTEHAVMRTLQARFNERRYFTNVGPILLSINPYLDVGNPLTLTST 529
            |||       ::|:..|| .|.|.||:..|..|:.....:|..|.||:::||:..:.:   |...
plant    52 PKDTEAPSEGVEDMTRLS-YLHEPAVLDNLATRYELNEIYTYTGNILIAVNPFQGLPH---LYDA 112

  Fly   530 RAM---------PLAPQLQKIVQEAVRQQSETGYPQAIILSGTSGAGKTANAMLMLRQLFAIAGG 585
            ..|         .|.|.:..|...|.|:....|..:.|::||.||:|||....:::|.| |..||
plant   113 EVMEKYKEAYFKELNPHVFAIGGIAYREMINEGRNKCILVSGESGSGKTETTKMLMRYL-AYFGG 176

  Fly   586 GPETD---AFKHLAAAFTVLRSLGSAKTTTNSESSRIGQFIEVQVTD-GALYRTKIHCYFLDQTR 646
            ....:   ....:..:..||.:.|:|||..|:.|||.|:|:|:|..| |.:....|..|.|:::|
plant   177 HTAVEGRTVENQVLESNPVLEAFGNAKTVKNNNSSRFGKFVEIQFDDVGRISGAAIRTYLLERSR 241

  Fly   647 VIRPLPKEKNYHIFYQLLAGLSRE-ERQKLHLDGYSPANLRYLRGDI-----GQNEQEDAARFQA 705
            |.:....|:|||.||.|.|....: ||.||.    .|.:.|||....     |.|   ||..:.|
plant   242 VCQVSDPERNYHCFYLLCAAPPEDVERFKLG----DPKSFRYLNQSSCYKLDGVN---DAEEYLA 299

  Fly   706 WKTCLGILGIPFLD---VVRVLAAVLLLGNVQFIDGGGLE-VDVKGET---ELNSVASLLGVPPA 763
            .:..:.::||...:   :.||:|::|.|||::|..|...: ..||.|.   .|...:.||...|.
plant   300 TRRAMDVVGISEKEQDAIFRVVASILHLGNIEFSKGEDADSSSVKDEQSMFHLQMTSELLMCDPH 364

  Fly   764 ALFRGLTTRTHNVRGQLVKSVCGDGDANMTRDCLAKALYCRTVATIVRRANSLKRLGSTLGTLSS 828
            :|...|..|......:::|.......|.::||.|||.:|.|....:|.:.|.         ::..
plant   365 SLEDALCKRMMVTPEEVIKRSLDPLGAAVSRDGLAKTIYSRLFDWLVNKINI---------SIGQ 420

  Fly   829 DSNESVHNQADVASQHASTIGGGNAGSKSMAALNNAVRHATSDGFIGILDMFGFEEPSPHAHLEH 893
            ||:                                      |...||:||::|||....:: .|.
plant   421 DSH--------------------------------------SRRLIGVLDIYGFESFKTNS-FEQ 446

  Fly   894 LCINLCAETMQHFYNTHIFKSSVESCRDEGIVCD-TEVDYVDNVPCIDLISSLRTGLLSMLDAEC 957
            .|||...|.:|..:|.|:||......:.|.|  | :.|::|||...:|||.....|::::||..|
plant   447 FCINYTNEKLQQHFNQHVFKMEQGEYQKEEI--DWSYVEFVDNKDVVDLIEKKPGGIIALLDEAC 509

  Fly   958 SV-RGTAESYVTKLKVQHRSSTRLETKPTAEPHDPRMFLIRHFAGRVEYDTTDFLDTNRDVVPDD 1021
            .: :.|.|::..||....:...|. .||.....|   |.:.|:||.|:|.:..|||.|:|.|
plant   510 MLPKSTPETFSEKLYHTFKDHKRF-MKPKLTRSD---FTLVHYAGDVQYQSDQFLDKNKDYV--- 567

  Fly  1022 LVGVFYKHTCNFGFATHLFGSELKALYAQQQAPRGLSFRISPTSHSDLLNGDE---------PV- 1076
                                                     ...|.||||..:         |:
plant   568 -----------------------------------------VAEHQDLLNASKCSFVSGLFPPLP 591

  Fly  1077 --------STLTQDFHTRLDNLLRTLVHARPHFVRCIRSNGTEAARSFDRATVVRQIRSLQVLET 1133
                    |::...|..:|..|:.||....||::||::.|.......||.|.|:.|:||..|||.
plant   592 KESSKSKFSSIGARFKLQLQQLMETLNSTEPHYIRCVKPNNLLQPTVFDNANVLHQLRSGGVLEA 656

  Fly  1134 VNLMASGFPHRMRFKQFNARYRMLAPFRLLRRSEDKALEDCQLILKYAMEQPPVLDGSVTLAWAP 1198
            :.:..:|:|....|.:|..|:.:|||..|      |...:.::..|:.:|:..:....:
plant   657 IRVKCAGYPTNRTFIEFLNRFLILAPEIL------KGEYEAEVACKWILEKKGLTGYQI------ 709

  Fly  1199 GKRHVFLSEGIRQHLEHLRTEIRHKSATL-----------------------MQATWRGWWWRKK 1240
            ||..|||..|....|:..||.:..:||.:                       :||.||
plant   710 GKSKVFLRAGQMAELDAHRTRVLGESARMIQGQVRTRLTRERFVLMRRASVNIQANWR------- 767

  Fly  1241 MGNGGAKRSKIPGLQQAPLPNNKT------------TPNSAAQNKAASSTMAA 1281
             ||...|.||....::|.:...|.            |.:||...::...||||
plant   768 -GNIARKISKEMRREEAAIKIQKNLRRQIAKKDYGKTKSSALTLQSGVRTMAA 819

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
d	NP_001188730.1	MYSc	476..1217	CDD:214580	210/786 (27%)
d	NP_001188730.1	MYSc_Myo20	488..1206	CDD:276847	202/763 (26%)
XIJ	NP_001319790.1	Myosin_N	9..46	CDD:397036
		MYSc_Myo11	74..717	CDD:276835	202/763 (26%)
		IQ	829..849	CDD:197470
		DUF460	<1081..>1142	CDD:421465
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0160
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D311886at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820