DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment d and XID

DIOPT Version :9

Sequence 1:	NP_001188730.1	Gene:	d / 34179	FlyBaseID:	FBgn0262029	Length:	1426	Species:	Drosophila melanogaster
Sequence 2:	NP_180882.2	Gene:	XID / 817886	AraportID:	AT2G33240	Length:	1770	Species:	Arabidopsis thaliana

Alignment Length:	800	Identity:	229/800 - (28%)
Similarity:	354/800 - (44%)	Gaps:	144/800 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   474 DMQDLIHLSGPLTEHAVMRTLQARFNERRYFTNVGPILLSINPYLDV----GNPL--TLTSTRAM 532
            ||..|.:|..|    .|:..|:||:|....:|..|.||:::||:..:    ||.:  ....|...
plant    82 DMTKLAYLHEP----GVLLNLKARYNANEIYTYTGNILIAVNPFKRLPHLYGNEIMEQYKGTDFG 142

  Fly   533 PLAPQLQKIVQEAVRQQSETGYPQAIILSGTSGAGKTANAMLMLRQLFAIAGGGPETD---AFKH 594
            .|:|....:...|.|:....|..|||::||.||||||.:.. ||.|..|..||..|::   ..:.
plant   143 ELSPHPFAVADSAYRKMINEGVSQAILVSGESGAGKTESTK-MLMQYLAYMGGKAESEGRSVEQQ 206

  Fly   595 LAAAFTVLRSLGSAKTTTNSESSRIGQFIEVQVT-----DGALYRTKIHCYFLDQTRVIRPLPKE 654
            :..:..||.:.|:|||..|:.|||.|:|:|:|..     .||..||    |.|:::||.:....|
plant   207 VLESNPVLEAFGNAKTVRNNNSSRFGKFVEIQFNHMGRISGAAIRT----YLLERSRVCQVSDPE 267

  Fly   655 KNYHIFYQLLAGLSRE-ERQKLHLDGYSPANLRYLRGDIGQNEQ--------EDAARFQAWKTCL 710
            :|||.||.|.|...:| ||.:|.    .|:...||      |:.        :|:..:.|.:..:
plant   268 RNYHCFYMLCAAPEQETERYQLG----KPSTFHYL------NQSNCHALDAIDDSKEYLATRKAM 322

  Fly   711 GILGIPFLD---VVRVLAAVLLLGNVQFI---DGGGLE-VDVKGETELNSVASLLGVPPAALFRG 768
            .::||...:   :.||:||:|.|||::|.   :..|.| .|.|....|...|.|......||...
plant   323 DVVGISPEEQDAIFRVVAAILHLGNIEFAKSEESDGAEPKDDKSRFHLKVAAKLFMCDEKALENS 387

  Fly   769 LTTRTHNVRGQLVKSVCGDGDANMTRDCLAKALYCRTVATIVRRANSLKRLGSTLGTLSSDSNES 833
            |..|....||:.:......|.|.::||.|||.:|.:....:|.:.|:         ::..||
plant   388 LCNRVMVTRGESITKPLDPGSAALSRDALAKIVYSKLFDWLVTKINN---------SIGQDS--- 440

  Fly   834 VHNQADVASQHASTIGGGNAGSKSMAALNNAVRHATSDGFIGILDMFGFEEPSPHAHLEHLCINL 898
                                               :|...||:||::|||....:: .|..||||
plant   441 -----------------------------------SSKYIIGVLDIYGFESFKTNS-FEQFCINL 469

  Fly   899 CAETMQHFYNTHIFKSSVESCRDEGIVCD-TEVDYVDNVPCIDLISSLRTGLLSMLDAECSV-RG 961
            ..|.:|..:|.|:||...|....|.|  | :.::::||...:|||.....|::::||..|.. |.
plant   470 TNEKLQQHFNQHVFKMEQEEYTKEEI--DWSYIEFIDNQDVLDLIEKKPGGIIALLDEACMFPRS 532

  Fly   962 TAESYVTKLKVQHRSSTRLETKPTAEPHDPRMFLIRHFAGRVEYDTTDFLDTNRDVVPDDLVGVF 1026
            |.::...||.....|..|. |||.....|   |.|.|:||.|.|.|..|||.|:|.|..:...:.
plant   533 THDTLAEKLYQTFGSHKRF-TKPKLARTD---FTICHYAGDVTYQTELFLDKNKDYVVGEHQSLM 593

  Fly  1027 YKHTCNFGFATHLFGSELKALYAQQQAPRGLSFRISPTSHSDLLNGDEPVSTLTQDFHTRLDNLL 1091
            ....|:  |.:.||..      :::::.:...|                 |::...|..:|.:||
plant   594 NSSDCS--FVSSLFPK------SREESSKSSKF-----------------SSIGSQFKQQLQSLL 633

  Fly  1092 RTLVHARPHFVRCIRSNGTEAARSFDRATVVRQIRSLQVLETVNLMASGFPHRMRFKQFNARYRM 1156
            .||....||::||::.|.......|:...|:.|:|...|:|.:.:..:|:|.|..|.:|..|:|:
plant   634 ETLNTTEPHYIRCVKPNNVLKPEIFENVNVLHQLRCGGVMEAIRISCAGYPTRKPFNEFLTRFRI 698

  Fly  1157 LAPFRLLRRSEDKALEDCQLILKYAMEQPPVLDGSVTL-AWAPGKRHVFLSEGIRQHLEHLRTEI 1220
            ||| ....||.|: ::.|:.:|           ..|.| .:..||..|||..|....|:..|.|:
plant   699 LAP-EATERSFDE-VDACKKLL-----------ARVDLKGFQIGKTKVFLRAGQMAELDAHRAEV 750

  Fly  1221 RHKSATLMQATWRGWWWRKK 1240
            ...||.::|.....:..|||
plant   751 LGHSARIIQRKVITYLSRKK 770

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
d	NP_001188730.1	MYSc	476..1217	CDD:214580	219/773 (28%)
d	NP_001188730.1	MYSc_Myo20	488..1206	CDD:276847	213/750 (28%)
XID	NP_180882.2	Myosin_N	28..64	CDD:280832
		MYSc	76..744	CDD:214580	220/772 (28%)
		MYSc_Myo11	92..736	CDD:276835	214/754 (28%)
		Tropomyosin_1	926..1068	CDD:289488
		PRKG1_interact	937..1023	CDD:292521
		MIS13	987..1241	CDD:285420
		MyosinXI_CBD	1298..1739	CDD:271259
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0160
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D311886at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820