DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment d and XIG

DIOPT Version :9

Sequence 1:	NP_001188730.1	Gene:	d / 34179	FlyBaseID:	FBgn0262029	Length:	1426	Species:	Drosophila melanogaster
Sequence 2:	NP_179619.2	Gene:	XIG / 816548	AraportID:	AT2G20290	Length:	1493	Species:	Arabidopsis thaliana

Alignment Length:	803	Identity:	220/803 - (27%)
Similarity:	356/803 - (44%)	Gaps:	133/803 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   469 NSSPKDMQ-------DLIHLSGPLTEHAVMRTLQARFNERRYFTNVGPILLSINPYLDVGNPLTL 526
            |:.||||:       |:..|: .|.|..|::.|::|:.....:|..|.||:::||:..:.|   |
plant    61 NTYPKDMEVPPSGVDDMTTLA-YLHEPGVLQNLKSRYYIDEIYTYTGNILIAVNPFKQLPN---L 121

  Fly   527 TSTRAM---------PLAPQLQKIVQEAVRQQSETGYPQAIILSGTSGAGKTANAMLMLRQLFAI 582
            .:...|         .|:|....:...|.||....|..|:|::||.||||||..|.::::.| |.
plant   122 YNDHMMAQYKGAALGELSPHPFAVADAAYRQMINEGISQSILVSGESGAGKTETAKMLMKYL-AK 185

  Fly   583 AGGGPETD---AFKHLAAAFTVLRSLGSAKTTTNSESSRIGQFIEVQVTD-GALYRTKIHCYFLD 643
            .||...:|   ....:..:..||.:.|:|||..|:.|||.|:|:|:|... |.:....|..|.|:
plant   186 MGGRAVSDRRTVEDQVLESNPVLEAFGNAKTVKNNNSSRFGKFVEIQFDQRGRISGAAIRTYLLE 250

  Fly   644 QTRVIRPLPKEKNYHIFYQLLAGLSREERQKLHLDGYSPANLRYLRGD--IGQNEQEDAARFQAW 706
            ::||.:....|:|||.||.|.|. ..|:::||.|:  .|...|||...  |..:..:|:..:...
plant   251 RSRVCQVSDPERNYHCFYMLCAA-PPEDKRKLKLN--DPTEFRYLNQSHCIKLDGVDDSKEYTKT 312

  Fly   707 KTCLGILGIPFLD---VVRVLAAVLLLGNVQFIDGGGLEVDVKGETE-----LNSVASLLGVPPA 763
            :..:||:||...:   :.||:||:|.|||::|..|.  |.|....|:     |...|.|......
plant   313 REAMGIVGINLEEQEAIFRVVAAILHLGNIEFAIGE--EPDSSVPTDESKKYLKIAAELFMCDEQ 375

  Fly   764 ALFRGLTTRTHNVRGQLVKSVCGDGDANMTRDCLAKALYCRTVATIVRRANSLKRLGSTLGTLSS 828
            ||...|..|......:.:........|.::||.|||.:|.|....||.:.|:
plant   376 ALEDSLCKRIMVTPEETISRCLDPNSAALSRDALAKFVYSRLFDWIVNKINN------------- 427

  Fly   829 DSNESVHNQADVASQHASTIGGGNAGSKSMAALNNAVRHATSDGFIGILDMFGFEEPSPHAHLEH 893
                |:               |.:..||.|               ||:||::|||....:: .|.
plant   428 ----SI---------------GQDPDSKDM---------------IGVLDIYGFESFKTNS-FEQ 457

  Fly   894 LCINLCAETMQHFYNTHIFKSSVESCRDEGIVCDTEVDYVDNVPCIDLISSLRTGLLSMLDAECS 958
            .||||..|.:|..:..|:.|...|....|.|.. :::.:.||...::||...|.|::::||..|.
plant   458 FCINLTNEKLQQHFTQHVLKMEQEEYTKEEIEW-SQITFPDNRYVLELIEKKRGGIIALLDEACM 521

  Fly   959 V-RGTAESYVTKLKVQHRSSTRLETKPTAEPHDPRMFLIRHFAGRVEYDTTDFLDTNRDVVPDDL 1022
            . |.|.:::..|| .:.....:..:||.....|   |.|.|:||.|.|.|..||:.|:|.|..:.
plant   522 FPRSTHKTFSQKL-YETLKDNKYFSKPKLSRTD---FTICHYAGDVTYQTEQFLEKNKDYVVAEH 582

  Fly  1023 VGVFYKHTCNFGFATHLFGSELKALYAQQQAPRGLSFRISPTSHSDLLNGDEPVSTLTQDFHTRL 1087
            ..:.....|.|          :..|:              |....| .|.....|::...|..:|
plant   583 QALLGASRCTF----------IAGLF--------------PPLVED-ANKQSKFSSIASQFKQQL 622

  Fly  1088 DNLLRTLVHARPHFVRCIRSNGTEAARSFDRATVVRQIRSLQVLETVNLMASGFPHRMRFKQFNA 1152
            .:|:..|....||::||::.|.......|:....::|:|...|:||:.:..:|:|.|..|.:|..
plant   623 ASLIEGLNTTEPHYIRCVKPNNLLKPSIFENQNSLQQLRCGGVMETIRVCRAGYPTRKHFDEFLD 687

  Fly  1153 RYRMLAPFRLLRRSEDKALEDCQLILKYAMEQPPVLDGSVTL-AWAPGKRHVFLSEGIRQHLEHL 1216
            |:.:|....|.:.|::||.  |:.:|:           :|.| .:..||..|||..|....|:..
plant   688 RFGILDSATLDKSSDEKAA--CKKLLE-----------TVGLNGFQIGKTKVFLKAGQMAELDDR 739

  Fly  1217 RTEIRHKSATLMQATWRGWWWRK 1239
            |||:..::|.::|..:|.:..|:
plant   740 RTEVLGRAACIIQWKFRSYLTRQ 762

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
d	NP_001188730.1	MYSc	476..1217	CDD:214580	208/772 (27%)
d	NP_001188730.1	MYSc_Myo20	488..1206	CDD:276847	201/742 (27%)
XIG	NP_179619.2	Myosin_N	23..58	CDD:280832
		MYSc	73..740	CDD:214580	208/767 (27%)
		MYSc_Myo11	86..729	CDD:276835	201/742 (27%)
		DUF4200	922..1052	CDD:290574
		MyosinXI_CBD	1112..1463	CDD:271259
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0160
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D311886at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820