Protein Alignment dachs and myo3b

DIOPT Version :10

• Sequence 1: NP_001188730.1
• Gene: dachs / 34179
• FlyBaseID: FBgn0262029
• Length: 1426
• Species: Drosophila melanogaster
• Sequence 2: XP_073768512.1
• Gene: myo3b / 564573
• ZFINID: ZDB-GENE-070706-2
• Length: 1333
• Species: Danio rerio
• Alignment Length: 1089
• Identity: 288/1089 - (26%)
• Similarity: 450/1089 - (41%)
• Gaps: 252/1089 - (23%)

  Fly   418 VGHHLSHAHSQQLPFIPQS--KHTNPCQSVKTLPFGFGFSESQQKMQQQQQQGN----------- 469
            |.|.|.|      |||.|:  |.|...|.:..|            :::||..|:
Zfish   326 VTHLLEH------PFIKQAHGKDTLLRQQLSVL------------IREQQDVGSRTKTRHERINT 372

  Fly   470 -------SSPKDMQDLIHLSGPLTEHAVMRTLQARFNERRYFTNVGPILLSINPYLDVGNPLTLT 527
                   |.|.|  ||::|. .|.|..::..||.|:.:.:.:|.||.||:::||:.:    |::.
Zfish   373 RKTLIIESCPDD--DLVNLE-LLDEETIIAHLQKRYQDLQIYTYVGDILIALNPFQN----LSIY 430

  Fly   528 STRAMPLAPQLQKIVQEAVRQ--------QSETGY--------PQAIILSGTSGAGKTANAMLML 576
            |       ||..|:.....|.        .::..|        .|.||:||.||||||.:|.|::
Zfish   431 S-------PQFSKLYHGMKRSTNPPHIFATADAAYQSMVTLCKDQCIIISGESGAGKTESAHLIV 488

  Fly   577 RQLFAIAGGGPETDAFKHLAAAFTVLRSLGSAKTTTNSESSRIGQFIEVQVT-DGALYRTKIHCY 640
            :.|..:......|...|.|... .::.:.|:|.|..|..|||.|:::|::.| .||:...||..|
Zfish   489 QHLTFLGKANNRTLREKILQVN-PLVEAFGNACTAINDNSSRFGKYLEMKFTPTGAVMGAKISEY 552

  Fly   641 FLDQTRVIRPLPKEKNYHIFYQLLAGLSREER-QKLHL-DGYSPANLRYLRGDIGQN-------- 695
            .|:::|||:....|||:||||.:.|||..::. :|..| :..:|..:..:.|.:.|:
Zfish   553 LLEKSRVIKQATGEKNFHIFYYIYAGLYHQDNLRKYKLPNKTAPRYIDCVNGKVMQDIISSKLYK 617

  Fly   696 EQEDAARFQAWKTCLGILGIPFLD-----VVRVLAAVLLLGNVQFIDGGGLEVDVKGET----EL 751
            ||     |.|.:.|..|:|  |.:     |.|:|||:|..||::|..........|.|.    .|
Zfish   618 EQ-----FDAIQDCFRIIG--FTEEEVNSVYRILAAILNTGNIEFASASSQHQSDKSEVPNSEAL 675

  Fly   752 NSVASLLGVPPAALFRGLTTRTHNVRGQLVKSVCGDGDANMTRDCLAKALYCRTVATIVRRANSL 816
            ::.|:||.:....|...||:.....||:.:........|.:.||.::||||.|..:.||.|.|:|
Zfish   676 DNAAALLSIGSEELQEALTSHCVVTRGETIIRTNTVDKATVVRDAMSKALYGRLFSWIVNRINAL 740

  Fly   817 KRLGSTLGTLSSDSNESVHNQADVASQHASTIGGGNAGSKSMAALNNAVRHATSDGFIGILDMFG 881
                     |..|:|                                 :..|.|...:||||:||
Zfish   741 ---------LQPDTN---------------------------------ICAAESGMNVGILDIFG 763

  Fly   882 FEEPSPHAHLEHLCINLCAETMQHFYNTHIFKSSVESCRDEGIVCDTE-VDYVDNVPCIDLISSL 945
            ||....:: .|.||||:..|.:|.::|.|||.......:.||:  |.. |:|.||.|.:|:....
Zfish   764 FENFKKNS-FEQLCINIANEQIQFYFNQHIFALEQIEYQSEGV--DVSLVEYEDNRPILDMFLQK 825

  Fly   946 RTGLLSMLDAECSV-RGTAESYVTKLKVQHRSS-----TRLETKPTAEPHDPRMFLIRHFAGRVE 1004
            ..||||:||.|... :.|.::.|.|.:...|:.     .|:|.          .|.|:|:||:|.
Zfish   826 PMGLLSLLDEESRFPQATDQTLVDKFQDNLRNKYFWIPKRVEL----------CFGIQHYAGQVL 880

  Fly  1005 YDTTDFLDTNRDVVPDDLVGVFYKHTCNFGFATHLFGSEL-----------------KALYAQQQ 1052
            |:.:.||:.|||.:|.|:|.|.  .|........||.|.|                 ::|..|..
Zfish   881 YNVSGFLEKNRDTLPADIVVVL--RTSENRLLQQLFSSPLTKTGNLATSRARVTAASRSLPPQLN 943

  Fly  1053 APRGLS--FRISPTSHSDLLNGDEPVS----TLTQDFHTRLDNLLRTLVHARPHFVRCIRSNGTE 1111
            :.|..|  :.:...:...:.:.:|..:    |:...|...|.:||..:|...|||||||:.|...
Zfish   944 SGRNKSPKYLLKVDTMEMMRHPEETTNMRRQTVASYFRYSLMDLLSKMVVGTPHFVRCIKPNDDR 1008

  Fly  1112 AARSFDRATVVRQIRSLQVLETVNLMASGFPHRMRFKQFNARYRMLAPFRLLRRSEDKALEDCQL 1176
            .|..|::..|:.|:|...:|||||:...|:.||:..::|..||..|| ||..:..|. :.|:..:
Zfish  1009 QALRFNKERVMVQLRYTGILETVNIRRQGYSHRILIQEFVNRYYYLA-FRAHQMPEG-SKENAII 1071

  Fly  1177 ILKYAMEQPPVLDGSVTLAWAPGKRHVFLSEGIRQHLEHLRTEIRHKSA--TLMQATWRGWWWRK 1239
            ||:.|.     ||     .|..|...|||.   ..|:|.|...:|...|  .||||..:||.
Zfish  1072 ILQKAK-----LD-----YWVVGNTKVFLK---YYHVEQLNLMLREVIARVVLMQAYTKGWL--- 1120

  Fly  1240 KMGNGGAKRSKIPGLQQAPLPNNKTTPNSAAQNKAASSTMAALAAVAAAAPISVPRLSAKTTSLG 1304
                 ||:|.:   .::....|......||.:...|...:..:......|.:.:       .|:.
Zfish  1121 -----GARRYR---REREKRRNGAVVIQSAWRGHVARQNLKLIKREREQAAVQI-------QSVY 1170

  Fly  1305 IGGTVARPRPQPIAGTPPPDPQEKC-----DQKIIQQTCNLFGLDLERPPPVPPSRSYTITGNSK 1364
            .|..|.:...|....|..|..:...     |:|::                       :::.:|.
Zfish  1171 RGYRVRKDYKQSRQWTGQPSSKRSSTNHSPDEKVV-----------------------SVSADSG 1212

  Fly  1365 ISYPQNRVMKMNFPEEGQSEAPQLKKGEAVTVVGASTVRGHLMVEHKGQ 1413
            |......|.|.:...:.:..||..|:|..:      .:..|.....:||
Zfish  1213 IGSSDASVPKTDKQSDSRERAPLSKQGPTL------KLHQHRSPRRRGQ 1255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dachs	NP_001188730.1	MYSc_Myo20	488..1206	CDD:276847	226/783 (29%)
		IQCD	1219..1250	CDD:467745	11/32 (34%)
myo3b	XP_073768512.1	None