Protein Alignment dachs and Myo61F

DIOPT Version :10

• Sequence 1: NP_001188730.1
• Gene: dachs / 34179
• FlyBaseID: FBgn0262029
• Length: 1426
• Species: Drosophila melanogaster
• Sequence 2: NP_476934.2
• Gene: Myo61F / 38153
• FlyBaseID: FBgn0010246
• Length: 1052
• Species: Drosophila melanogaster
• Alignment Length: 914
• Identity: 247/914 - (27%)
• Similarity: 395/914 - (43%)
• Gaps: 196/914 - (21%)

  Fly   457 SQQKMQ----QQQQQGNSSPKDMQDLIHLSGPLTEHAVMRTLQARFNERRYFTNVGPILLSINPY 517
            ||.||:    ::.:.|      :||.:.|....:|.|.:..|:.||.|...:|.:|.:|:|:|||
  Fly    23 SQLKMETGLHERDRAG------VQDFVLLENYQSEEAFIGNLKKRFQEDLIYTYIGQVLISVNPY 81

  Fly   518 LDVGNPL-TLTSTRA--------MPLAPQLQKIVQEAVRQQSETGYPQAIILSGTSGAGKTANAM 573
            ..:  |: |....:|        ||  |.:..:...|.|...|....|.:::||.||:|||..:.
  Fly    82 KQL--PIYTDDHVKAYRNKHFYEMP--PHIFAVTDNAFRSLIEENRGQCVLISGESGSGKTEASK 142

  Fly   574 LMLRQLFAIAGGGPETDAFK-HLAAAFTVLRSLGSAKTTTNSESSRIGQFIEVQVT-DGALYRTK 636
            .:|:.:.|.:|.....:..| .|..:..||.:.|:|||..|..|||.|:::::|.. .||.....
  Fly   143 KVLQFIAACSGNQTTVEGVKDKLLKSNPVLEAFGNAKTNRNDNSSRFGKYMDIQFDFKGAPIGGN 207

  Fly   637 IHCYFLDQTRVIRPLPKEKNYHIFYQLLAG----LSREERQKLHLDGYSPANLRYLRGDIG--QN 695
            |..|.|:::||:..:..|:|:|||||||||    |.:|.|.:..||.||     ||...:.  ..
  Fly   208 ILNYLLEKSRVVAQMGGERNFHIFYQLLAGADEALLQELRLERALDTYS-----YLTDGLNGTVT 267

  Fly   696 EQEDAARFQAWKTCLGILGIPFL-----DVVRVLAAVLLLGNVQFIDGGGLEVDVKGETELNS-- 753
            ...||..|:..:..|.:  |.|.     ::..::|::|.||||.|       .:|:|..::||
  Fly   268 RINDADSFKQVQQALTV--IDFTKEEQREIFGIVASILHLGNVGF-------TEVEGNAKVNSRD 323

  Fly   754 ----VASLLGVPPAALFRGLTTRTHNVRGQLVKSVCGDGDANMTRDCLAKALYCRTVATIVRRAN 814
                .|.||||..:.|...||.||.:.||.:|.|......|...||.||||:|.|..:.:|:|.|
  Fly   324 LVVTAARLLGVNASELEAALTHRTIDARGDVVTSPLNQELAIYARDALAKAVYDRLFSWLVQRLN 388

  Fly   815 SLKRLGSTLGTLSSDSNESVHNQADVASQHASTIGGGNAGSKSMAALNNAVRHATSDGFIGILDM 879
                       :|..:.|                        :.|:.||.         :||||:
  Fly   389 -----------ISLQAKE------------------------TRASRNNV---------MGILDI 409

  Fly   880 FGFEEPSPHAHLEHLCINLCAETMQHFYNTHIFKSSVESCRDEGIVCDTEVDYVDNVPCIDLISS 944
            :|||....:: .|..|||.|.|.:|..:.....||..:..|.|||.. ..|:|.||....:||..
  Fly   410 YGFEIFQKNS-FEQFCINFCNEKLQQLFIELTLKSEQDEYRREGIEW-IPVEYFDNKVICNLIEE 472

  Fly   945 LRTGLLSMLDAECSVRG--TAESYVTKLK---VQHRSSTRLETKPTAEPHDPRM-----FLIRHF 999
            ...|::|:||.||...|  |.::::.||.   .||......|..|.   |..::     |.:.|:
  Fly   473 KHKGIISILDEECLRPGEPTDKTFLEKLTQKLAQHHHYVCHEKAPA---HIKKIMLRDEFRLVHY 534

  Fly  1000 AGRVEYDTTDFLDTNRDVVPDDLVGVFYKHTCNFGFATHLFGSELKALYAQQQAPRGLSFRISPT 1064
            ||.|.|....|||.|.|::..||     |.|.:                   :|..|:.....|
  Fly   535 AGEVTYSVNGFLDKNNDLLFRDL-----KETLS-------------------KAGNGIVRNCFP- 574

  Fly  1065 SHSDLLNGDEPVSTLTQDFHTRLDNLLRTLVHARPHFVRCIRSNGTEAARSFDRATVVRQIRSLQ 1129
             ..:|.:...|.:.:|| |...|:||:..|:...|.::|||:.|..:.|..|:...|:.|::.|.
  Fly   575 -EKELRSLKRPETAITQ-FRASLNNLMDILMCKEPSYIRCIKPNDLQTANVFNDELVLHQVKYLG 637

  Fly  1130 VLETVNLMASGFPHRMRFKQFNARYRMLA------------PFRLLRRSEDKALEDCQLILKYAM 1182
            ::|.:.:..:||.:|..::.|..||:.|:            |    :....:.::|    |.:..
  Fly   638 LMENLRVRRAGFAYRRTYELFLERYKSLSKSTWPNYKGPGGP----KAGVQQLVKD----LGWDE 694

  Fly  1183 EQPPVLDGSVTLAWAPGKRHVFLSEGIRQHLEHLRTEIRHKSATLMQATWRGW------------ 1235
            |:..|.:..:.:.|   .|.:|.:|...|       |.:|:.|.::||.|:|.
  Fly   695 EKYRVGETKLFIRW---PRTLFDTEDAYQ-------EKKHEIAAIIQAHWKGLMQRRKYLKLRAQ 749

  Fly  1236 ------WWRKKMGNGGAKR-----SKIPGLQQAPLPNNKTTPNSAAQNKAASSTMAALAAVAAAA 1289
                  :.|:|:....||:     .||....:..:..| ..||...:...|::....|..:|...
  Fly   750 VIIMQSYCRRKLAQQAAKKRREAADKIRAFIKGFITRN-DAPNGFNEEFIANAKRMWLLRLAKEL 813

  Fly  1290 PISV 1293
            |..|
  Fly   814 PTKV 817

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dachs	NP_001188730.1	MYSc_Myo20	488..1206	CDD:276847	215/767 (28%)
		IQCD	1219..1250	CDD:467745	11/53 (21%)
Myo61F	NP_476934.2	MYSc_Myo1	52..707	CDD:276829	212/756 (28%)
		Myosin_TH1	863..1049	CDD:461801