Protein Alignment dachs and Myo5c

DIOPT Version :10

• Sequence 1: NP_001188730.1
• Gene: dachs / 34179
• FlyBaseID: FBgn0262029
• Length: 1426
• Species: Drosophila melanogaster
• Sequence 2: XP_006243475.1
• Gene: Myo5c / 315820
• RGDID: 1309994
• Length: 1749
• Species: Rattus norvegicus
• Alignment Length: 793
• Identity: 235/793 - (29%)
• Similarity: 358/793 - (45%)
• Gaps: 117/793 - (14%)

  Fly   477 DLIHLSGPLTEHAVMRTLQARFNERR-YFTNVGPILLSINPYLDV---GNPL--TLTSTRAMPLA 535
            ||..|| .|.|.||:..|:.||.|.: .:|..|.||:::|||..:   |:.:  ..:......:.
  Rat    71 DLTALS-YLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQNMGDMD 134

  Fly   536 PQLQKIVQEAVRQQSETGYPQAIILSGTSGAGKTANAMLMLRQLFAIAGGGPETDAFKHLAAAFT 600
            |.:..:.:||.:|.:.....|:||:||.||||||.:|...:|....::.........:.:.|:..
  Rat   135 PHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSSSNAHVEEKVLASNP 199

  Fly   601 VLRSLGSAKTTTNSESSRIGQFIEVQVTD-----GALYRTKIHCYFLDQTRVIRPLPKEKNYHIF 660
            :..::|:||||.|..|||.|::.|:...:     ||..||    |.|:::||:.....|:|||||
  Rat   200 ITEAVGNAKTTRNDNSSRFGKYTEISFDERNQIIGANMRT----YLLEKSRVVFQSENERNYHIF 260

  Fly   661 YQLLAGLSREERQKLHLDGYSPANLRYLRGDI---GQNEQEDAARFQAWKTCLGILGIPFLDVVR 722
            |||.|...:.|.:.|.|......|...:.|:.   |.:::.|.|..|...|.||......:||.:
  Rat   261 YQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVDDRADMAETQKTFTLLGFKKDFQMDVFK 325

  Fly   723 VLAAVLLLGNVQFIDGGGLEVDV-KGETELNSVASLLGVPPAALFRGLTTRTHNVRGQLVKSVCG 786
            :|||:|.|||||....|.....| :.::.|.....|||:....:.:.|..|......:.|.....
  Rat   326 ILAAILHLGNVQVTTVGNERSAVSEDDSHLKVFCELLGLETIKVAQWLCNRKIVTSSETVVKPMT 390

  Fly   787 DGDANMTRDCLAKALYCRTVATIVRRANSLKRLGSTLGTLSSDSNESVHNQADVASQHASTIGGG 851
            ...|...||.|||.:|......||.:.                 |:::|..   ..||.
  Rat   391 RPQAINARDALAKKIYAHLFDFIVEQI-----------------NQALHFS---GKQHT------ 429

  Fly   852 NAGSKSMAALNNAVRHATSDGFIGILDMFGFEEPSPHAHLEHLCINLCAETMQHFYNTHIFKSSV 916
                                 |||:||::|||....:: .|..|||...|.:|..:|.|:||...
  Rat   430 ---------------------FIGVLDIYGFETFDVNS-FEQFCINYANEKLQQQFNLHVFKLEQ 472

  Fly   917 ESCRDEGIVCDTEVDYVDNVPCIDLISSLRTGLLSMLDAECSV-RGTAESYVTKLKVQHRSSTRL 980
            |....|.|.. |.:|:.||.|.||||.: :.|:|.:||.||.: .||.|:::.||.....:...|
  Rat   473 EEYMKEDIPW-TLIDFYDNQPVIDLIEA-KMGILELLDEECLLPHGTDENWLQKLYNNFVNKNSL 535

  Fly   981 ETKPTAEPHDPRM----FLIRHFAGRVEYDTTDFLDTNRDVVPDDLVGVFYK---HTCNFGF--- 1035
            ..|       |||    |:|:|||.:|||....||:.|||.|.|.||.|...   |.|...|
  Rat   536 FEK-------PRMSNSSFIIQHFADKVEYQCEGFLEKNRDTVYDMLVEVLRASKFHLCAAFFQES 593

  Fly  1036 --ATHLFGSELKALYAQQQ-APRGLSFRISPTSHSDLLNGDEPVSTLTQDFHTRLDNLLRTLVHA 1097
              .:..||:.:....|:|. .|....||                :|:...|.:.|..|:.||...
  Rat   594 PVPSSPFGAMITVKSAKQVIKPNTKHFR----------------TTVGNKFRSSLFLLMETLNAT 642

  Fly  1098 RPHFVRCIRSNGTEAARSFDRATVVRQIRSLQVLETVNLMASGFPHRMRFKQFNARYRMLAPFRL 1162
            .||:||||:.|..:....||...:|:|:|:..||||:.:.|..:|.|..:.:|.:||.:|...:.
  Rat   643 TPHYVRCIKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYLEFYSRYGVLMTQQE 707

  Fly  1163 LRRSEDKALEDCQLILKYAMEQPPVLDGSVTLAWAPGKRHVFLSEGIRQHLEHLRTEIRHKSATL 1227
            |..|:.|  |.|:::|...::.        :..:..|:..:|...|...:||.||.:...:...:
  Rat   708 LSLSDKK--EVCKVVLHRLIQD--------SNQYQFGRTKIFFRAGQVAYLEKLRLDKLRQGCIV 762

  Fly  1228 MQATWRGWWWRKK 1240
            :|...|||..|||
  Rat   763 IQKHVRGWLQRKK 775

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dachs	NP_001188730.1	MYSc_Myo20	488..1206	CDD:276847	217/746 (29%)
		IQCD	1219..1250	CDD:467745	7/22 (32%)
Myo5c	XP_006243475.1	MYSc_Myo5	81..741	CDD:276831	217/746 (29%)
		IQ	755..776	CDD:197470	7/21 (33%)
		IQ	831..851	CDD:459869
		SMC_prok_B	<850..>1385	CDD:274008
		Myo5c_CBD	1376..1743	CDD:271260