DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dachs and rasip1

DIOPT Version :10

Sequence 1:NP_001188730.1 Gene:dachs / 34179 FlyBaseID:FBgn0262029 Length:1426 Species:Drosophila melanogaster
Sequence 2:NP_001276809.1 Gene:rasip1 / 102725533 ZFINID:ZDB-GENE-120403-3 Length:989 Species:Danio rerio


Alignment Length:683 Identity:127/683 - (18%)
Similarity:196/683 - (28%) Gaps:277/683 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly   320 SGSGGGGGAGGGAVVSARNTSIPHPLPH---QLAEKPGLSHQQSGSGHGQSTGTLPHMSGMGSIL 381
            |....||||........||:.:...:..   .|..:.|            :||..|..||...  
Zfish   284 SRMSSGGGAEEERGHRGRNSELRRSISDMNLSLRRRQG------------NTGNDPRRSGCAQ-- 334

  Fly   382 GQNSHSHAPVNNNSNNSNTLPMRTSNSGHLGINGGGVGHHLSHAH--------------SQQLPF 432
                      ||..:..|.:.|..:..|.:..:.|||........              ||.|..
Zfish   335 ----------NNGQDRKNIVSMIATEGGEVSGSRGGVSESDRRTRVAEEDKDTCDLEVMSQSLIL 389

  Fly   433 IP-------------QSK---------HTNPCQSVKTLPFGFGFSESQQKMQQQQQQGNSSPKDM 475
            .|             |||         ||:        .||...:..:::|.:::::....|..:
Zfish   390 PPTDRPYFLLLQGYDQSKDFVLYIMAGHTH--------VFGRKPTFREREMDREREKKGKRPLKV 446

  Fly   476 QDLIHLSGP--LTEHAVMR------------TLQARFNERRYFTNVGPI----LLSINPYLDVGN 522
            .  .:||.|  |..|.::|            .|...|...:...|..|:    :|.....|.:|:
Zfish   447 D--TYLSAPDLLARHLLIRRDTAVPEQPHGQALARPFRGGQATLNGAPLYREAVLKPGDLLGLGS 509

  Fly   523 PL-------TLTSTRAMPLAPQLQKIV------------QEAVR-----QQSETGYP-------- 555
            ..       .:|....:.|.|..|..:            ||.:|     .:|...|.        
Zfish   510 HFLFLYRDPRVTPVPPLALPPPWQGDMPTSFGPGGMTDRQEMLRLYLGSTESLLRYQAKHADALL 574

  Fly   556 QAIILSGT---SGAGKTANAMLMLRQL-FAIAGGGPETDAFKHLAAAFTV-------LRSLGSAK 609
            |.|||..|   ||.|..|.|.|:...: :|.....||......|.||..:       ::..|...
Zfish   575 QEIILKNTSPDSGGGALAPAYLLSLMIDYASKHLDPELTPQLLLKAANQIKGIVWDKIKEFGDKH 639

  Fly   610 TTTNSESSRIG---------------------------QFIEVQV-------------------- 627
            .|.||..:.:.                           .|.:|:|                    
Zfish   640 PTQNSADAEVDLPPPSAQKLSSDLRPLMFWMSNATELLNFFQVKVEALEKEWEFEAPGDPVLSAD 704

  Fly   628 ----------TDGALYRTKIHC-YFLDQTRVIRPLPKEKNYHIFYQLLAGL------SREERQKL 675
                      .|..:..|...| |.|.:|              .|.||..|      |.|||:| 
Zfish   705 MDTCSEALAQLDDVIMHTFQQCVYHLTKT--------------LYSLLPALLDTNPFSSEERKK- 754

  Fly   676 HLDGYSPANLRYLRGDIGQNEQEDAARFQAWKTCLGILGIPFLDVVRVLAAVLLLGNVQFIDGGG 740
                 :.|.::...|..|:.::|:                                     ||..
Zfish   755 -----AKAGVKDKTGSGGEGDEEE-------------------------------------DGSA 777

  Fly   741 LEVDVKGETELNSVASLLGVPPAALFRGLTTRTHN-----VRGQLVKSVCGDGDANMTRDCL--- 797
            |...|.|..|:.. .||.....|.|...||::|..     ....|:.::       :.||.|   
Zfish   778 LPPTVAGLVEVYR-CSLQLSREACLSPPLTSQTFGYLFFFTNTSLLNTL-------LERDNLFSW 834

  Fly   798 AKALYCRTVATIVRRANSLKRL-GSTLGTLSSD 829
            ::|:..||...:|     |..| |:.||.::|:
Zfish   835 SRAVQIRTNLDLV-----LDWLQGAGLGDIASE 862

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dachsNP_001188730.1 MYSc_Myo20 488..1206 CDD:276847 88/474 (19%)
IQCD 1219..1250 CDD:467745
rasip1NP_001276809.1 Ubl1_cv_Nsp3_N-like 138..254 CDD:475130
FHA_RAIN 392..518 CDD:438786 22/135 (16%)
Myo5p-like_CBD_Rasip1 568..945 CDD:271256 70/365 (19%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.