Protein Alignment prg and Zbtb4

DIOPT Version :10

• Sequence 1: NP_609232.2
• Gene: prg / 34177
• FlyBaseID: FBgn0285971
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_083624.2
• Gene: Zbtb4 / 75580
• MGIID: 1922830
• Length: 982
• Species: Mus musculus
• Alignment Length: 271
• Identity: 64/271 - (23%)
• Similarity: 92/271 - (33%)
• Gaps: 94/271 - (34%)

  Fly   108 GLNGNPGVFVPEEGCIIVEVDPENLAESSEEEFALG--SDGEYENYDDDDEEEEEDYDEEDEEDG 170
            ||......:||.....:|..||      :|:....|  :|||:..
Mouse   156 GLGEGGDTWVPPAPTSMVTSDP------TEDGLGAGPRTDGEWVG-------------------- 194

  Fly   171 QNGEDVDMPLGMDAAQMAAQQSVANNANTTEARPKRAFLCQYCDLGFTLPAECQEHEL------- 228
                        |.|:          |.|.:::|:|.|.|..|...|..|...|.||.
Mouse   195 ------------DKAE----------ALTPDSQPRRPFPCPRCGKSFIHPKRLQTHEAQCRRGSN 237

  Fly   229 -----------------AAHDPNA-PYCCNFCN-----IKLVTRPALISHIKTLHDPDRPYVCAH 270
                             |..|.:| |....|.:     :|:|....|             ||||.
Mouse   238 TRGSAGLGPGVSGSGGPAGVDASALPQPVGFRDGPEHVVKVVGGHVL-------------YVCAA 289

  Fly   271 CRKGFVRRSDLKKHTIVHTGVRPFTCNVCSKSFSRNTNLTKHMRIHSGVKPFVCQQCPRSFQTAV 335
            |.:.:|..|.||:|:.||:..|.:.|..|.|.|:.....|||...|:|.:.:.|..|..:|.|..
Mouse   290 CERSYVTLSSLKRHSNVHSWRRKYPCRYCEKVFALAEYRTKHEVWHTGERRYQCIFCWDTFVTYY 354

  Fly   336 EMMRHTRS-HG 345
            .:..|.|: ||
Mouse   355 NLKTHQRAFHG 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prg	NP_609232.2	zf-AD	16..94	CDD:462262
		COG5048	<212..340	CDD:227381	40/157 (25%)
		C2H2 Zn finger	239..260	CDD:275368	4/25 (16%)
		C2H2 Zn finger	268..288	CDD:275368	8/19 (42%)
		C2H2 Zn finger	296..316	CDD:275368	7/19 (37%)
		C2H2 Zn finger	324..344	CDD:275368	6/20 (30%)
		C2H2 Zn finger	352..372	CDD:275368
		C2H2 Zn finger	416..436	CDD:275368
		C2H2 Zn finger	443..464	CDD:275368
		C2H2 Zn finger	470..490	CDD:275368
Zbtb4	NP_083624.2	BTB_POZ_ZBTB4	12..160	CDD:349504	2/3 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	71..103
		Interaction with CBFA2T3. /evidence=ECO:0000250|UniProtKB:Q9P1Z0	165..324		49/219 (22%)
		zf-C2HC_2	211..233	CDD:464037	7/21 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	234..255		0/20 (0%)
		C2H2 Zn finger	287..307	CDD:275368	8/19 (42%)
		C2H2 Zn finger	315..335	CDD:275368	7/19 (37%)
		C2H2 Zn finger	343..361	CDD:275368	5/17 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	404..578
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	591..700
		C2H2 Zn finger	704..722	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	715..738
		zf-C2H2	739..761	CDD:395048
		C2H2 Zn finger	741..761	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	759..839
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	854..880