DRSC/TRiP Functional Genomics Resources

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Protein Alignment prg and si:ch211-79k12.2

DIOPT Version :10

Sequence 1:NP_609232.2 Gene:prg / 34177 FlyBaseID:FBgn0285971 Length:558 Species:Drosophila melanogaster
Sequence 2:NP_001313520.1 Gene:si:ch211-79k12.2 / 568844 ZFINID:ZDB-GENE-131121-535 Length:555 Species:Danio rerio


Alignment Length:277 Identity:81/277 - (29%)
Similarity:127/277 - (45%) Gaps:40/277 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   210 CQYCDLGFTLPAECQEHELAAHDPNA-PYCCNFCNIKLVTRPALISHIKTLHDPDRPYVCAHCRK 273
            |.:|:..|..|::..:|:...|...| .:.|..|.....:...|..|: .:|...|||:|.:|.|
Zfish   281 CMHCNASFPRPSQLLQHQRTQHATKAGGFLCAECGRAFNSHSNLRIHL-NVHTGARPYICTNCGK 344

  Fly   274 GFVRRSDLKKHTIVHTGVRPFTCNVCSKSFSRNTNLTKHMRIHSGVKPFVCQQCPRSFQTAVEMM 338
            .|.:...||.|..:|||.||:||:.|.:.|.....:..|.|||:|.||::|.||.:.|..:..:.
Zfish   345 SFSQSGALKIHRRIHTGERPYTCSYCGRGFPHLAGVRAHQRIHTGEKPYICGQCGKCFTQSGALK 409

  Fly   339 RHTRSHGEVKAFQCGRCPYSFSRRDKL-IAHQQVHTRRDMEQQQQMGLIPPME-GDLQQQALQAK 401
            .|||.|...:.|.||.|..|||.|..: ..|:.||           |::  || ..:.:.:|.| 
Zfish   410 IHTRIHTGERPFVCGLCGKSFSNRSGIRFHHRTVH-----------GIV--MEPNSVGRPSLAA- 460

  Fly   402 QKAAAQTKNSRYYHCDVCDRTFQR---ERDLQRHQAL---------HMDSL---FACKTCNQGF- 450
             .|::|..:.:.......::...|   ||:|...:.:         :.|.|   :||:.|.|.| 
Zfish   461 -SASSQVSDIQRVQVSAVNQIHFRQIEERNLPSKELVQPSKEQLSGNADKLALPYACEDCGQRFP 524

  Fly   451 -----NRREQLQRHELE 462
                 ||.:.||.:.||
Zfish   525 DAPSRNRHQTLQHYSLE 541

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
prgNP_609232.2 zf-AD 16..94 CDD:462262
COG5048 <212..340 CDD:227381 41/128 (32%)
C2H2 Zn finger 239..260 CDD:275368 4/20 (20%)
C2H2 Zn finger 268..288 CDD:275368 7/19 (37%)
C2H2 Zn finger 296..316 CDD:275368 5/19 (26%)
C2H2 Zn finger 324..344 CDD:275368 7/19 (37%)
C2H2 Zn finger 352..372 CDD:275368 8/20 (40%)
C2H2 Zn finger 416..436 CDD:275368 4/31 (13%)
C2H2 Zn finger 443..464 CDD:275368 10/26 (38%)
C2H2 Zn finger 470..490 CDD:275368
si:ch211-79k12.2NP_001313520.1 SUF4-like 281..>331 CDD:411020 11/50 (22%)
C2H2 Zn finger 281..302 CDD:411020 5/20 (25%)
C2H2 Zn finger 281..302 CDD:275368 5/20 (25%)
C2H2 Zn finger 311..331 CDD:411020 4/20 (20%)
C2H2 Zn finger 311..331 CDD:275368 4/20 (20%)
zf-C2H2 337..359 CDD:395048 8/21 (38%)
C2H2 Zn finger 339..359 CDD:275368 7/19 (37%)
zf-H2C2_2 351..374 CDD:463886 11/22 (50%)
C2H2 Zn finger 367..387 CDD:275368 5/19 (26%)
zf-C2H2 393..415 CDD:395048 7/21 (33%)
C2H2 Zn finger 395..415 CDD:275368 7/19 (37%)
zf-H2C2_2 407..432 CDD:463886 10/24 (42%)
C2H2 Zn finger 423..442 CDD:275368 8/18 (44%)
Blue background indicates that the domain is not in the aligned region.

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