Protein Alignment prg and CG8301

DIOPT Version :10

• Sequence 1: NP_609232.2
• Gene: prg / 34177
• FlyBaseID: FBgn0285971
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_649915.1
• Gene: CG8301 / 41160
• FlyBaseID: FBgn0037717
• Length: 607
• Species: Drosophila melanogaster
• Alignment Length: 591
• Identity: 135/591 - (22%)
• Similarity: 209/591 - (35%)
• Gaps: 163/591 - (27%)

  Fly    14 VSTCR-------LCHHNTDPNSLNIFDDTVQFCKDVSIAEVSKSL--WSVQYDRNECLSELICSR 69
            :.|||       :|......|:.:..|.....|....:|::....  |:::...|:.|.:.|||.
  Fly     1 METCRTCAISMFVCDFENGSNNSHFLDLHHPNCWPSEMAQIRLQFANWNLKISPNDGLPQKICSD 65

  Fly    70 CLEILEEAFELRKGMQEREQSL--------------QEQLKEMIKDHPKHRPGLNGNPGVFVPEE 120
            |..........|...||.:..|              .|..:|.::...:|:......|...|.
  Fly    66 CFTKFCSINAFRLACQEAQLKLSHIYDKIDASSLEDDEIGQEDLEPAEEHQETETTKPTTTVS-- 128

  Fly   121 GCIIVEVDPENLAESSEEEFALGSDGEYENYDDDDEEEEEDYDEEDEEDGQNGEDVDMPLGMDAA 185
                .|..|.|.|....|.|.       :..|.|:.||||   ||:|:..|..|:|:.|:
  Fly   129 ----AETQPNNTASDPIEIFV-------DAVDIDEAEEEE---EEEEQQQQYDEEVEEPI----- 174

  Fly   186 QMAAQQSVANNANTTEARPKR---AFLCQYC---DLGFTLPAECQEHELAAHDPNAPY------- 237
                         |.|:.|.:   ::.|::|   ...:.|.....||..|:|||..||
  Fly   175 -------------TDESAPPQLTISYACKFCLRPQENYQLQQLLLEHINASHDPEQPYNCPECEA 226

  Fly   238 -------------------------C------------------------CNFCNIKLVTRPALI 253
                                     |                        |..|..:..||.:|.
  Fly   227 RFQDAASRTVHLKSSHVEKQHACGVCGKKYGDRHNLRHHVEKYHSETDFECALCEKRFYTRKSLN 291

  Fly   254 SHIKTLHDPDRPYVCAH--CRKGFVRRSDLKKHTIVHTGV---RPFTCNVCSKSFSRNTNLTKHM 313
            .|:| .|:|||.:.|.|  |.:.|:.:..|..|...|:|.   :...|..|.|:|.....|..|:
  Fly   292 YHMK-WHNPDRQFKCRHSGCERLFISQRHLMCHEATHSGTSSRKSEHCGFCGKTFIHLKTLRWHI 355

  Fly   314 -RIHSGVKPFVCQQCPRSFQTAVE-----MMRHTRSHGEVKAFQCGRCPYSFSRRDKLIAHQQVH 372
             |.|.|.||:.|..|...|.:..|     :.||..:...::..:|..|...||....||.|...
  Fly   356 YRQHGGEKPYKCANCTEVFASYAEKRIHMLERHRENLTAIERSECMLCRQPFSSEPDLIHHMSA- 419

  Fly   373 TRRDMEQQQQMGLIPPMEGDLQQQALQAKQKAAAQTKNSRYY----HCDVCDRTFQRERDLQRHQ 433
                 |..|:.|           ..:.|..|...|.|..|.|    .|..|.:.|..:..|:||.
  Fly   420 -----EHLQRPG-----------APIIANNKRVLQQKRERQYSGLFQCGSCSQRFNMKSALERHA 468

  Fly   434 ALH--MDSLFACKTCNQGFNRREQLQRHELEAH---GPSFTCGICCISFLHQIELENHLKVHQLQ 493
            |:|  .|...||..|::.|.|.:.::.| ::.|   .|: .|.:|..:|    .|:..|..|:|.
  Fly   469 AVHSEKDRPHACPHCSKRFKRAQDMKWH-IKTHEKEKPN-VCDVCGKAF----ALKYVLTQHRLS 527

  Fly   494 HKMAQR 499
            |::.::
  Fly   528 HEVLEK 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prg	NP_609232.2	zf-AD	16..94	CDD:462262	19/100 (19%)
		COG5048	<212..340	CDD:227381	45/197 (23%)
		C2H2 Zn finger	239..260	CDD:275368	7/20 (35%)
		C2H2 Zn finger	268..288	CDD:275368	6/21 (29%)
		C2H2 Zn finger	296..316	CDD:275368	7/20 (35%)
		C2H2 Zn finger	324..344	CDD:275368	6/24 (25%)
		C2H2 Zn finger	352..372	CDD:275368	7/19 (37%)
		C2H2 Zn finger	416..436	CDD:275368	7/19 (37%)
		C2H2 Zn finger	443..464	CDD:275368	5/20 (25%)
		C2H2 Zn finger	470..490	CDD:275368	5/19 (26%)
CG8301	NP_649915.1	zf-AD	3..88	CDD:462262	18/84 (21%)
		COG5048	198..>508	CDD:227381	79/329 (24%)
		C2H2 Zn finger	221..241	CDD:275368	0/19 (0%)
		C2H2 Zn finger	249..269	CDD:275368	1/19 (5%)
		C2H2 Zn finger	277..297	CDD:275368	7/20 (35%)
		C2H2 Zn finger	305..327	CDD:275368	6/21 (29%)
		C2H2 Zn finger	338..359	CDD:275368	7/20 (35%)
		C2H2 Zn finger	367..384	CDD:275368	4/16 (25%)
		C2H2 Zn finger	400..420	CDD:275368	7/25 (28%)
		C2H2 Zn finger	451..471	CDD:275368	7/19 (37%)
		C2H2 Zn finger	480..500	CDD:275368	5/20 (25%)
		C2H2 Zn finger	508..528	CDD:275368	7/23 (30%)
		SUF4-like	536..>586	CDD:411020
		C2H2 Zn finger	537..558	CDD:411020
		C2H2 Zn finger	537..557	CDD:275368
		C2H2 Zn finger	565..586	CDD:411020
		C2H2 Zn finger	565..582	CDD:275368