Protein Alignment prg and Meics

DIOPT Version :10

• Sequence 1: NP_609232.2
• Gene: prg / 34177
• FlyBaseID: FBgn0285971
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_524062.1
• Gene: Meics / 39539
• FlyBaseID: FBgn0025874
• Length: 583
• Species: Drosophila melanogaster
• Alignment Length: 603
• Identity: 146/603 - (24%)
• Similarity: 239/603 - (39%)
• Gaps: 146/603 - (24%)

  Fly     8 MTQDQDVS---TCRLCHHNTDPNSLNIFDDTVQFCKDVSIAEVSKSLWSV-----QYDRNECLSE 64
            |.:..|.|   .||.|..::     :|..|.  |.|::|...:.:.|.|:     :..|:| :.:
  Fly     9 MERSVDASMGKNCRACAEHS-----SILVDL--FSKEISDPPIWEMLNSILPEICRVKRDE-MPQ 65

  Fly    65 LICSRCLEILEEAFELRKGMQEREQSLQ--EQLKEMIKDHP----KHRPGLNGNPGVFVPEE--G 121
            .||..||...:.||..|   .:.|||.|  .||.::.|.:.    .|......||  .:|.|  |
  Fly    66 KICPTCLVAAQNAFHFR---HKCEQSFQFFSQLLQLDKSNSNLSRSHCRRGTMNP--LIPFEIVG 125

  Fly   122 C------IIVEVD---PE---NLAESSEEEFALGSDGE---------------------YENYDD 153
            |      .:.::|   |:   ::.|.::.:...|.:.|                     .|.::|
  Fly   126 CEDPLDTNVTKLDANRPDVKTDIDEPTDGKATNGQESEPLQEVFEITMNDIKTEDEVSIQETFED 190

  Fly   154 --DDEEEEEDYDEEDEEDGQ----NGEDVDMPL-----------GMDAAQMAAQQSVANNANTTE 201
              |:|.:..:.|.|.|:..|    :.||.|.|.           |.:.:.:..:..|:.:.....
  Fly   191 AFDEENDNNNTDSEREDSDQWTVGSTEDQDEPWIPGGGGRQTVGGNNQSLLCTECGVSYSTQKAL 255

  Fly   202 AR----------PKRAFLCQYCDLGFTLPAECQEH---------------------------ELA 229
            ||          .::..||.:|..||...|:...|                           .:.
  Fly   256 ARHVAKHKEQGDTQKPHLCDFCGRGFRTNAQLTTHRRRHTGERPFKCPLCPKAYTHGPTLKSHMH 320

  Fly   230 AHDPNAPYCCNFCNIKLVTRPALISHIKTLHDPDRPYVCAHCRKGFVRRSDLKKHTIVHTGVRPF 294
            .||....:.|..|:....||..|.:||:. |..:|||.|..|.:.|.:.|.||.|:.:|...|||
  Fly   321 THDEEKGHKCPQCDKTFYTRGNLRAHIQR-HTGERPYKCPDCPQTFAKNSGLKLHSRLHKEERPF 384

  Fly   295 TCNVCSKSFSRNTNLTKHMRIHSGVKPFVCQQCPRSFQTAVEMMRHTRSHGEVKAFQCGRCPYSF 359
            .|.:|.|.|.:|.:|..|:|:|:|.:.|.|..|.:||.....||:|.|:|..:|.|:|..|..:|
  Fly   385 KCELCGKGFVQNQHLITHLRVHNGDRQFKCPDCDKSFFEKSNMMKHQRTHSGIKPFKCEECGQAF 449

  Fly   360 SRRDKLIAHQQVHTRRDMEQQQQMGLIPPMEGDLQQQALQAKQKAAAQT-----KNSRYYHCDVC 419
            |....|.:|.::||.....:..|.|           :...|.|.....|     .|.|.:.|..|
  Fly   450 SHNHHLKSHLRIHTGEKPYKCDQCG-----------KGFSANQSLMKHTLWHVDNNDRPFKCSQC 503

  Fly   420 DRTFQRERDLQRHQALHMD-----SLFACKTCNQGFNRREQLQR----HELEAHGPSFTCGICCI 475
            .:.:..::.|:.|:..|.:     :|..|..|:..|..::.|.:    |::..|    .|..|..
  Fly   504 PKAYDTQQSLRGHEKTHKNPDEPKTLHQCPHCDVRFALKKTLDKHITSHKIRPH----PCPQCPE 564

  Fly   476 SFLHQIELENHLKVHQLQ 493
            .|..|..|:.||::|.|:
  Fly   565 GFFSQKSLKKHLRLHNLK 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prg	NP_609232.2	zf-AD	16..94	CDD:462262	23/84 (27%)
		COG5048	<212..340	CDD:227381	46/154 (30%)
		C2H2 Zn finger	239..260	CDD:275368	7/20 (35%)
		C2H2 Zn finger	268..288	CDD:275368	7/19 (37%)
		C2H2 Zn finger	296..316	CDD:275368	8/19 (42%)
		C2H2 Zn finger	324..344	CDD:275368	8/19 (42%)
		C2H2 Zn finger	352..372	CDD:275368	6/19 (32%)
		C2H2 Zn finger	416..436	CDD:275368	4/19 (21%)
		C2H2 Zn finger	443..464	CDD:275368	5/24 (21%)
		C2H2 Zn finger	470..490	CDD:275368	7/19 (37%)
Meics	NP_524062.1	zf-AD	20..95	CDD:462262	23/85 (27%)
		C2H2 Zn finger	242..262	CDD:275368	3/19 (16%)
		C2H2 Zn finger	274..294	CDD:275368	6/19 (32%)
		SFP1	<296..374	CDD:227516	19/78 (24%)
		COG5048	<299..486	CDD:227381	58/198 (29%)
		C2H2 Zn finger	302..322	CDD:275368	0/19 (0%)
		C2H2 Zn finger	330..350	CDD:275368	7/20 (35%)
		C2H2 Zn finger	358..378	CDD:275368	7/19 (37%)
		C2H2 Zn finger	386..406	CDD:275368	8/19 (42%)
		COG5048	<395..583	CDD:227381	54/203 (27%)
		C2H2 Zn finger	414..434	CDD:275368	8/19 (42%)
		C2H2 Zn finger	442..462	CDD:275368	6/19 (32%)
		C2H2 Zn finger	470..486	CDD:275368	4/26 (15%)
		C2H2 Zn finger	500..520	CDD:275368	4/19 (21%)
		C2H2 Zn finger	532..552	CDD:275370	4/19 (21%)
		C2H2 Zn finger	559..579	CDD:275370	7/19 (37%)