Protein Alignment prg and CG11906

DIOPT Version :10

• Sequence 1: NP_609232.2
• Gene: prg / 34177
• FlyBaseID: FBgn0285971
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_611402.2
• Gene: CG11906 / 37209
• FlyBaseID: FBgn0034425
• Length: 634
• Species: Drosophila melanogaster
• Alignment Length: 637
• Identity: 119/637 - (18%)
• Similarity: 193/637 - (30%)
• Gaps: 165/637 - (25%)

  Fly    10 QDQDVSTCRLCHHNTDPNSLNIFDDTVQFCKDVSIAEVSKSL---------------WSVQYDRN 59
            ||||.:... .....:.|..|        |.....|:.|..|               |.:..|..
  Fly    26 QDQDENHVG-AEREAEANDAN--------CTVCGAAKASALLDLRSNHVMQRRLSRDWKIHADVI 81

  Fly    60 ECLSELICSRCLEILEEAFELRKGMQEREQSLQEQLKEMIKDHPKHRPGLNGNPGVFVPEEGCII 124
            ....:.||..|:..|....|:.:.:.:|.|.||....|..|...........:|.:...|....:
  Fly    82 RSTLKAICVECVCKLNMHSEVTRSLMQRMQRLQRSGGETTKVTTTTTSPSQHSPPIADAEVSTTL 146

  Fly   125 VEVDPENLAESSEEEFALGSDGEYE------NYDDDDEEEEEDYDE--------EDEEDG----- 170
            :| ..|.:|.|.:...:..|....|      .|....:|.||.:.|        |..|.|
  Fly   147 IE-SQEEVAHSGQSVRSRSSCSVLEVYLAQQPYSPSAKETEEKHAEGWKWRTRLECHECGRAYFR 210

  Fly   171 -----QNGEDVDMPLGMDAAQMAAQQSVANNANTTEARPKRA------FLCQYCDLGFTLPAECQ 224
                 |:.................:..|.|.|:..|..|.||      :.|::||..|......:
  Fly   211 RDYYAQHLRRCSKTRRKQPRPSRVKCRVLNEASYDEEAPSRAIRSSRIYYCRHCDAEFETLISKR 275

  Fly   225 EHELAAHDPNAPYCCNFCNIKLVTRPALISHIKTLHDPDRPYVCAHCRKGFVRRSDLKKHTIVHT 289
            :||...|....|  |:.|..:|.|:.....|    |.     :|...::........:....|.|
  Fly   276 QHERMKHQQRYP--CDLCEAQLDTKYEWEMH----HT-----ICQAKQEALAIVEQQEAGQTVMT 329

  Fly   290 GVRPFTCNVCSKS---------------------------------------FSRNTNLT----- 310
            ...|..|::.|:|                                       ::|..|.|
  Fly   330 SRVPRACSMRSRSRACSEAWDRYDMDEEEEDEEDEEIESGGEELEEGEEDAMYARRMNFTGDWIV 394

  Fly   311 KHMRIHS----------GVKPFVCQQCPRSFQTAVEMMRHTRSHGEVKAFQC--GRCPYSFSRRD 363
            .|.|.:|          |....|........:..:.::...::...:|:|.|  ..|.|   :.|
  Fly   395 NHSRSNSNSAGNLSLLYGDYGMVETHMTTDKEYDLYLLDLLKTQVRLKSFTCFTPDCGY---QTD 456

  Fly   364 KLIAHQQVHTRRDMEQQQQMGLIPPMEGDLQQQALQAKQKAAAQTKNSRYYHCDVCDRTFQRERD 428
            .|:|..    :.|..:..:|.                            :::|..|...|..:..
  Fly   457 TLVALM----KHDYMEHWKMS----------------------------WFYCHKCGDVFTSKVF 489

  Fly   429 LQRHQALHMDSLFACKTCNQGFNRREQLQRH-ELEAHGPSFTCGICCISFLHQIELENHLKVHQL 492
            |..|..|....|:.|..|.:.|..:.||.|| :|...|.::.|..|.:.||.:.:|..|.|
  Fly   490 LDYHMHLQNRGLYICHKCREEFELQHQLDRHFQLHRKGINYHCNFCRLEFLSEAKLLAHCK---- 550

  Fly   493 QHKMAQRAQEAAILPLKMAEKAPVAMTAPLVQDPQLVRPSAAELSFYSNMIP 544
              |:.....:..::.:..: .:.|....|...|...:..|..|..||...||
  Fly   551 --KLGHSPNDEPLISIDRS-LSIVNCHVPRSSDYSRIVKSYEEREFYIPRIP 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prg	NP_609232.2	zf-AD	16..94	CDD:462262	17/92 (18%)
		COG5048	<212..340	CDD:227381	28/181 (15%)
		C2H2 Zn finger	239..260	CDD:275368	5/20 (25%)
		C2H2 Zn finger	268..288	CDD:275368	1/19 (5%)
		C2H2 Zn finger	296..316	CDD:275368	8/63 (13%)
		C2H2 Zn finger	324..344	CDD:275368	0/19 (0%)
		C2H2 Zn finger	352..372	CDD:275368	6/21 (29%)
		C2H2 Zn finger	416..436	CDD:275368	5/19 (26%)
		C2H2 Zn finger	443..464	CDD:275368	8/21 (38%)
		C2H2 Zn finger	470..490	CDD:275368	7/19 (37%)
CG11906	NP_611402.2	None