DRSC/TRiP Functional Genomics Resources

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Protein Alignment prg and Paris

DIOPT Version :10

Sequence 1:NP_609232.2 Gene:prg / 34177 FlyBaseID:FBgn0285971 Length:558 Species:Drosophila melanogaster
Sequence 2:NP_608840.1 Gene:Paris / 33657 FlyBaseID:FBgn0031610 Length:346 Species:Drosophila melanogaster


Alignment Length:449 Identity:113/449 - (25%)
Similarity:188/449 - (41%) Gaps:109/449 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 CRLCHHNTDPNSLNIFDDTVQFCKDVSIAEVSKSLWSVQYDRNECLSELICSRCLEILEEAFELR 81
            ||:| .:.....:||||  .:....|||||:.......:..|.:..||:||.:|.|.::.|:.:|
  Fly     5 CRVC-MDISGKLVNIFD--ARRRTRVSIAEMIAQCTGFEVKRGDLFSEMICPQCYEDVKSAYGIR 66

  Fly    82 KGMQEREQSLQEQLKEMIKDHPKHRPGLNGNPGVFVPEEGCIIVEVDPENLAESSEEEFALGSDG 146
            :..:|..|.......|.|:|                  ..|.::                     
  Fly    67 QTCEESHQFYCRVRDEGIED------------------ALCALL--------------------- 92

  Fly   147 EYENYDDDDEEEEEDYDEEDEEDGQNGEDVDMPLGMDAAQMAAQQSVANNANTTEARPKRAFLCQ 211
                       ||||::..::||.:          :|:|      |.|::...:::: |.||.|:
  Fly    93 -----------EEEDWEISEDEDAR----------IDSA------SAADDDGKSDSK-KVAFECR 129

  Fly   212 YCDLGFTLPAECQEHELAAHDPNAPYCCNFCNIKLVTRPALISHIKTLHDPDRPYVCAHCRKGFV 276
            .|...:........| :..|.....:.|.:|......|..|.:|:|| |:..:||.|:||.|.|.
  Fly   130 ECHKKYQRKGTFLRH-MRTHMDGQSFPCPYCKRNFRLRVTLKAHMKT-HNAAKPYECSHCAKTFA 192

  Fly   277 RRSDLKKHTIVHTGVRPFTCNVCSKSFSRNTNLTKHMRIHSGVKPFVCQQCPRSFQTAVEMMRHT 341
            ::|.|:.|...|||.|||.|:.|||:|.::::|.:|:|.|...:||.|.:|.::|.....:..|.
  Fly   193 QQSTLQSHERTHTGERPFKCSQCSKTFIKSSDLRRHIRTHGSERPFKCSKCTKTFTRKFHLDNHF 257

  Fly   342 RSHGEVKAFQCGRCPYSFSRRDKLIAHQQVHTRRDMEQQQQMGLIPPMEGDLQQQALQAKQKAAA 406
            |||...:.|:|..||.:|:.:..|..|.::|             :|                   
  Fly   258 RSHTGERPFKCSHCPKAFAMKQHLKQHSRLH-------------LP------------------- 290

  Fly   407 QTKNSRYYHCDVCDRTFQRERDLQRHQALH-MDSLFACKTCNQGFNRREQLQRHELEAH 464
                .|.:.|..|.:||:....|:.|:.:| .:..|.|..|...:.:|:.|.||.||.|
  Fly   291 ----DRPFRCSHCPKTFRLSSTLKEHKLVHNAERTFKCPHCASFYKQRKTLARHILEIH 345

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
prgNP_609232.2 zf-AD 16..94 CDD:462262 23/76 (30%)
COG5048 <212..340 CDD:227381 41/127 (32%)
C2H2 Zn finger 239..260 CDD:275368 7/20 (35%)
C2H2 Zn finger 268..288 CDD:275368 8/19 (42%)
C2H2 Zn finger 296..316 CDD:275368 8/19 (42%)
C2H2 Zn finger 324..344 CDD:275368 5/19 (26%)
C2H2 Zn finger 352..372 CDD:275368 6/19 (32%)
C2H2 Zn finger 416..436 CDD:275368 6/19 (32%)
C2H2 Zn finger 443..464 CDD:275368 8/20 (40%)
C2H2 Zn finger 470..490 CDD:275368
ParisNP_608840.1 zf-AD 4..78 CDD:462262 23/75 (31%)
C2H2 Zn finger 128..148 CDD:275368 3/20 (15%)
C2H2 Zn finger 156..176 CDD:275368 7/20 (35%)
COG5048 <180..341 CDD:227381 57/196 (29%)
C2H2 Zn finger 184..204 CDD:275368 8/19 (42%)
C2H2 Zn finger 212..232 CDD:275368 8/19 (42%)
C2H2 Zn finger 240..260 CDD:275368 5/19 (26%)
C2H2 Zn finger 268..288 CDD:275368 6/19 (32%)
C2H2 Zn finger 296..316 CDD:275368 6/19 (32%)
C2H2 Zn finger 324..341 CDD:275368 5/16 (31%)
Blue background indicates that the domain is not in the aligned region.

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