Protein Alignment prg and ZBTB38

DIOPT Version :10

• Sequence 1: NP_609232.2
• Gene: prg / 34177
• FlyBaseID: FBgn0285971
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: XP_047303797.1
• Gene: ZBTB38 / 253461
• HGNCID: 26636
• Length: 1236
• Species: Homo sapiens
• Alignment Length: 362
• Identity: 86/362 - (23%)
• Similarity: 138/362 - (38%)
• Gaps: 87/362 - (24%)

  Fly    63 SELICSRCLEILEEAFELRKGMQEREQSLQEQLKEMIKDHPKHRPGLNGNPGVFVPEEGCIIVEV 127
            :|.|..|  .||......::|.:.:.|..:|.|.:             ||
Human   886 NEAIVKR--HILGSKLFYKRGRRPKYQMQEEPLPQ-------------GN--------------- 920

  Fly   128 DPE-------NLAESSEEEFALGSDGEYENYDDDDEEEEED------YDEEDEEDGQN------- 172
            |||       .|.:|...|.:       |.:||..:::..|      |:.:.::..:.
Human   921 DPEPSGDSPLGLCQSECMEMS-------EVFDDASDQDSTDKPWRPYYNYKPKKKSRQLKKMRKV 978

  Fly   173 -----------GEDVDMPLGMDAAQMAAQQSVANNANTTEARPKRAFLCQYCDLGFTLPA--ECQ 224
                       ......|..:|.|...|.|........|:..||  ..|:.||....:.|  :.:
Human   979 NWRKEHGNRSPSHKCKYPAELDCAVGKAPQDKPFEEEETKEMPK--LQCELCDGDKAVGAGNQGR 1041

  Fly   225 EHELAAHDPNAPYCCNFCNIKLVTRPALISHIKTLHDPDRPYVCAHCRKGFVRRSDLKKHTIVHT 289
            .|.   |..:.||.|..|..:..:...|..|:: .|..::||.|..|.:.|..:.:|:||..:|.
Human  1042 PHR---HLTSRPYACELCAKQFQSPSTLKMHMR-CHTGEKPYQCKTCGRCFSVQGNLQKHERIHL 1102

  Fly   290 GVRPFTCNVCSKSFSRNTNLTKHMRIHSGVKPFVCQQCPRSFQTAVEM-------MRHTRSHGEV 347
            |::.|.|..|:|:|:.|..|..|.|||:|.|.:.||.|   ||..:.:       .||.|.|..
Human  1103 GLKEFVCQYCNKAFTLNETLKIHERIHTGEKRYHCQFC---FQRFLYLSTKRNHEQRHIREHNG- 1163

  Fly   348 KAFQCGRCPYSFSRRDKLIAHQQVHTRRDMEQQQQMG 384
            |.:.|.:||........|..||:.|..:...||:::|
Human  1164 KGYACFQCPKICKTAAALGMHQKKHLFKSPSQQEKIG 1200

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prg	NP_609232.2	zf-AD	16..94	CDD:462262	7/30 (23%)
		COG5048	<212..340	CDD:227381	40/136 (29%)
		C2H2 Zn finger	239..260	CDD:275368	4/20 (20%)
		C2H2 Zn finger	268..288	CDD:275368	6/19 (32%)
		C2H2 Zn finger	296..316	CDD:275368	8/19 (42%)
		C2H2 Zn finger	324..344	CDD:275368	8/26 (31%)
		C2H2 Zn finger	352..372	CDD:275368	6/19 (32%)
		C2H2 Zn finger	416..436	CDD:275368
		C2H2 Zn finger	443..464	CDD:275368
		C2H2 Zn finger	470..490	CDD:275368
ZBTB38	XP_047303797.1	BTB_POZ_ZBTB38_CIBZ	56..169	CDD:349532
		zf-C2H2_8	<373..443	CDD:464935
		C2H2 Zn finger	385..405	CDD:275368
		C2H2 Zn finger	414..433	CDD:275368
		C2H2 Zn finger	503..523	CDD:275368
		C2H2 Zn finger	531..551	CDD:275368
		C2H2 Zn finger	559..577	CDD:275368
		C2H2 Zn finger	1053..1073	CDD:275368	4/20 (20%)
		zf-H2C2_2	1066..1089	CDD:463886	7/23 (30%)
		zf-C2H2	1079..1101	CDD:395048	7/21 (33%)
		C2H2 Zn finger	1081..1101	CDD:275368	6/19 (32%)
		C2H2 Zn finger	1109..1129	CDD:275368	8/19 (42%)
		zf-H2C2_2	1122..>1140	CDD:463886	9/17 (53%)
		C2H2 Zn finger	1137..1161	CDD:275368	8/26 (31%)