Protein Alignment prg and ZNF280B

DIOPT Version :10

• Sequence 1: NP_609232.2
• Gene: prg / 34177
• FlyBaseID: FBgn0285971
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_542942.2
• Gene: ZNF280B / 140883
• HGNCID: 23022
• Length: 543
• Species: Homo sapiens
• Alignment Length: 182
• Identity: 47/182 - (25%)
• Similarity: 69/182 - (37%)
• Gaps: 32/182 - (17%)

  Fly   210 CQYCDLGFTLPAECQEHELAAHDPNAP-YCCNFCNIKLVTRPALISHIKTLHDPDRPYVCAHCRK 273
            ||:|...|..|.:.|.|....|....| ..|..|.:...|...|:.|:|..|.|
Human   345 CQHCHRQFPTPFQLQCHIENVHTAQEPSTVCKICELSFETDQVLLQHMKDHHKP----------- 398

  Fly   274 GFVRRSDLKKHTIVHTGVRPFTCNVCSKSFSRNTNLTKHMR-IHSGVKPFVCQQCPRSFQTAVEM 337
                            |..|:.|.||....|...::..|.| .|...|..:|..|.:.|:||...
Human   399 ----------------GEMPYVCQVCHYRSSVFADVETHFRTCHENTKNLLCPFCLKIFKTATPY 447

  Fly   338 MRHTRSHGEVKAFQCGRCPYSF-SRRDKLIAHQQVHTRRDMEQQQQMGLIPP 388
            |.|.|.|....|.||.:|...| :.::|:....|.|  :..::.:|:..:||
Human   448 MCHYRGHWGKSAHQCSKCRLQFLTFKEKMEHKTQCH--QMFKKPKQLEGLPP 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prg	NP_609232.2	zf-AD	16..94	CDD:462262
		COG5048	<212..340	CDD:227381	31/129 (24%)
		C2H2 Zn finger	239..260	CDD:275368	6/20 (30%)
		C2H2 Zn finger	268..288	CDD:275368	0/19 (0%)
		C2H2 Zn finger	296..316	CDD:275368	6/20 (30%)
		C2H2 Zn finger	324..344	CDD:275368	8/19 (42%)
		C2H2 Zn finger	352..372	CDD:275368	5/20 (25%)
		C2H2 Zn finger	416..436	CDD:275368
		C2H2 Zn finger	443..464	CDD:275368
		C2H2 Zn finger	470..490	CDD:275368
ZNF280B	NP_542942.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23
		DUF4195	45..226	CDD:463993
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	105..138
		C2H2 Zn finger	345..366	CDD:275368	7/20 (35%)
		C2H2 Zn finger	375..395	CDD:275368	6/19 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	518..543