DRSC/TRiP Functional Genomics Resources

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Protein Alignment Agpat2 and Lpcat4

DIOPT Version :10

Sequence 1:NP_609231.2 Gene:Agpat2 / 34176 FlyBaseID:FBgn0026718 Length:271 Species:Drosophila melanogaster
Sequence 2:NP_997089.1 Gene:Lpcat4 / 99010 MGIID:2138993 Length:524 Species:Mus musculus


Alignment Length:254 Identity:67/254 - (26%)
Similarity:110/254 - (43%) Gaps:46/254 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 CVVALILSATAKAPYQMRMFFIFFGAGLIVFLCVPFMILR----PRDYRNALFPSW----CF--- 65
            |::.::|     ||.::.:.||      ::||..||..|:    ..:........|    |.   
Mouse    40 CLLGVLL-----APIRVLLAFI------VLFLLWPFAWLQVAGLTEEQLQEPITGWRKTVCHNGV 93

  Fly    66 ----RQLCRLVG-ITMEVRGLENVRKDHGAVVIMNHQSAVDLCVLAYLWPVIGRATVVSKKEVLY 125
                |.|..|:| :.:.|||....|.:...:|...|.:..|..||.    ......|||:.|.|.
Mouse    94 LGLSRLLFFLLGFLRIRVRGQRASRLEAPVLVAAPHSTFFDPIVLL----PCDLPKVVSRAENLS 154

  Fly   126 IPFFGIGAWLWGTLYIDRSRKTDSINSLQKEAKAIQERNC------KLLLFPEGTRNSKDSLLPF 184
            :|.  |||.|.....|..||...:  |.::..:.::.|..      ::|.|||||.::|.:||.|
Mouse   155 VPV--IGALLRFNQAILVSRHDPA--SRRRVVEEVRRRATSGGKWPQVLFFPEGTCSNKKALLKF 215

  Fly   185 KKGSFHIALQGKSPVQPVVISKYSFMDDEKKTFRPGHALIHILPEVSTEKYKREDVQLL 243
            |.|:|...:    |||||:|...:.:|.....:| |..::.:|...:::.....||:.|
Mouse   216 KPGAFIAGV----PVQPVLIRYPNSLDTTSWAWR-GPGVLKVLWLTASQPCSIVDVEFL 269

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Agpat2NP_609231.2 PlsC 47..261 CDD:439974 58/219 (26%)
Lpcat4NP_997089.1 LPLAT_LPCAT1-like 109..306 CDD:153253 50/174 (29%)
HXXXXD motif 129..134 1/4 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 490..524
Blue background indicates that the domain is not in the aligned region.

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