DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Agpat2 and LPCAT1

DIOPT Version :9

Sequence 1:	NP_001162912.1	Gene:	Agpat2 / 34176	FlyBaseID:	FBgn0026718	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	XP_011512434.1	Gene:	LPCAT1 / 79888	HGNCID:	25718	Length:	571	Species:	Homo sapiens

Alignment Length:	212	Identity:	57/212 - (26%)
Similarity:	95/212 - (44%)	Gaps:	51/212 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 VRGLENVRKDHGAVVIMNHQSAVDLCVLAYLWPV-IGRATVVSKKEVLYIPFFGIGAWLWGTL-- 139
            |:|.:.:..:...:.:..|.|..|..      || :..:::|.|.|...||       :||||
Human   154 VKGRQALPTEAAILTLAPHSSYFDAI------PVTMTMSSIVMKAESRDIP-------IWGTLIQ 205

  Fly   140 -----YIDRSRKTDSINSLQKEAKAIQERNCK---LLLFPEGTRNSKDSLLPFKKGSFHIALQGK 196
                 ::.||.: ||.....:|.|...:.|.|   :::|||||..::..|:.||.|:|   :.|
Human   206 YIRPVFVSRSDQ-DSRRKTVEEIKRRAQSNGKWPQIMIFPEGTCTNRTCLITFKPGAF---IPG- 265

  Fly   197 SPVQPVVISKYSFMDDEKKTFRPGHAL---------------IHILPEVS-TEKYKR------ED 239
            :||||||:...:.:|....|::...||               |..||..| :|:.||      .:
Human   266 APVQPVVLRYPNKLDTITWTWQGPGALEILWLTLCQFHNQVEIEFLPVYSPSEEEKRNPALYASN 330

  Fly   240 VQLLIDECQSIMQTEYT 256
            |:.::.|...:..|:||
Human   331 VRRVMAEALGVSVTDYT 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat2	NP_001162912.1	LPLAT_AGPAT-like	65..248	CDD:153251	54/202 (27%)
LPCAT1	XP_011512434.1	PlsC	95..>279	CDD:223282	41/142 (29%)
		LPLAT_LPCAT1-like	140..351	CDD:153253	57/212 (27%)
		EF-hand_7	458..516	CDD:290234
		EF-hand_8	469..520	CDD:290545
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810