DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Agpat2 and Lpcat2b

DIOPT Version :9

Sequence 1:	NP_001162912.1	Gene:	Agpat2 / 34176	FlyBaseID:	FBgn0026718	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_081875.1	Gene:	Lpcat2b / 70902	MGIID:	1918152	Length:	516	Species:	Mus musculus

Alignment Length:	257	Identity:	56/257 - (21%)
Similarity:	114/257 - (44%)	Gaps:	41/257 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ACTCEVIG-------LACVVALILSATAKAPYQMRMFFIFFGAGLIVFLCVPFMILRP-RDYRNA 58
            |||. ::|       ::|:|.|::              :.:...::..:.:|....:| |.:|..
Mouse    52 ACTI-ILGTVLVPVRVSCIVFLLI--------------LLWPVAVLSAINLPTQPTKPIRRWRKH 101

  Fly    59 LFPS---WCFRQLCRLVGITMEVRGLENVRKDHGAVVIMNHQSAVDLCVLAYLWPVIGRATVVSK 120
            |..|   :.||......|..::|:|.:..|::....|...|.:..|...:.    |.|..:|||.
Mouse   102 LIKSALVFLFRLGFFFAGFLVKVKGKKATREEAPIFVSAPHSTFFDAIAVV----VAGLPSVVSD 162

  Fly   121 KEVLYIPFFGIGAWLWGTLYIDR----SRKTDSINSLQKEAKAIQERNCKLLLFPEGTRNSKDSL 181
            .::..:|..|....:...:.:.|    |||| :.|.:.:..|: :.:..::|:||||...::..|
Mouse   163 SQLARVPLAGKCILVTQPVLVKREDPNSRKT-TRNEILRRVKS-KMKWPQILIFPEGLCTNRSCL 225

  Fly   182 LPFKKGSFHIALQGKSPVQPVVISKYSFMDDEKKTFRPGHALIHILPEVSTEKYKREDVQLL 243
            :.||.|:|...:    |||||::...:.:|....|:. |.:...:.....::.:.|.:|:.:
Mouse   226 VTFKLGAFSPGV----PVQPVLLRYPNSLDTVTWTWN-GFSGFQVCMLTLSQLFTRVEVEFM 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat2	NP_001162912.1	LPLAT_AGPAT-like	65..248	CDD:153251	43/183 (23%)
Lpcat2b	NP_081875.1	PlsC	65..307	CDD:223282	52/243 (21%)
		LPLAT_LPCAT1-like	111..323	CDD:153253	43/183 (23%)
		HXXXXD motif	142..147		1/4 (25%)
		EFh	392..454	CDD:238008
		EF-hand_7	392..453	CDD:290234
		EFh	429..487	CDD:298682
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810