DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Agpat2 and AGPAT3

DIOPT Version :9

Sequence 1:	NP_001162912.1	Gene:	Agpat2 / 34176	FlyBaseID:	FBgn0026718	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	XP_011527964.1	Gene:	AGPAT3 / 56894	HGNCID:	326	Length:	463	Species:	Homo sapiens

Alignment Length:	340	Identity:	83/340 - (24%)
Similarity:	128/340 - (37%)	Gaps:	109/340 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 CTCEVI------GLACVVALILSATAKAPYQMRMF-------FIFFGAGLI---VFLCVPFMILR 51
            |.||.:      ....|..|:.||.....:....|       |:|..:||:   |.||.
Human    64 CVCEPLEKDGCPQRGAVHPLLSSAMGLLAFLKTQFVLHLLVGFVFVVSGLVINFVQLCT------ 122

  Fly    52 PRDYRNALFP--SWCFRQL-CRLV-------------------GITMEVRGLENVRKDHGAVVIM 94
                 .||:|  ...:|:| |||.                   .:..:...:|...|:| ||:|:
Human   123 -----LALWPVSKQLYRRLNCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVERFGKEH-AVIIL 181

  Fly    95 NHQSAVD-LC--VLAYLWPVIGRATVVSKKEVLYIPFFGIGAWLWGTLYI---------DRSRKT 147
            ||...:| ||  .:...:.|:|.:.|::|||:||:|..|   |.|..|.|         ||....
Human   182 NHNFEIDFLCGWTMCERFGVLGSSKVLAKKELLYVPLIG---WTWYFLEIVFCKRKWEEDRDTVV 243

  Fly   148 DSINSLQKEAKAIQERNCKLLLFPEGTRNS-------------------KDSLLPFKKGSFHIAL 193
            :.:..|....:.:.     .||:.||||.:                   |..|||..|| |..|:
Human   244 EGLRRLSDYPEYMW-----FLLYCEGTRFTETKHRVSMEVAAAKGLPVLKYHLLPRTKG-FTTAV 302

  Fly   194 QGKSPVQPVVISKYSFMDDEKKTFR--PGHALIHIL------PEVSTEKYKREDVQLLIDECQSI 250
            :   .::..|.:.|    |....||  ...:|:.||      .::...::..||:.|  ||.::.
Human   303 K---CLRGTVAAVY----DVTLNFRGNKNPSLLGILYGKKYEADMCVRRFPLEDIPL--DEKEAA 358

  Fly   251 MQTEYTKLSKEGQAL 265
            ....  ||.:|..||
Human   359 QWLH--KLYQEKDAL 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat2	NP_001162912.1	LPLAT_AGPAT-like	65..248	CDD:153251	60/241 (25%)
AGPAT3	XP_011527964.1	PLN02380	104..412	CDD:178006	75/300 (25%)
		LPLAT_LCLAT1-like	149..343	CDD:153252	50/210 (24%)
		Acyltransf_C	330..401	CDD:292694	12/46 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810