DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Agpat2 and lpgat1

DIOPT Version :9

Sequence 1:	NP_001162912.1	Gene:	Agpat2 / 34176	FlyBaseID:	FBgn0026718	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_001025129.1	Gene:	lpgat1 / 561832	ZFINID:	ZDB-GENE-030131-2906	Length:	371	Species:	Danio rerio

Alignment Length:	214	Identity:	54/214 - (25%)
Similarity:	88/214 - (41%)	Gaps:	45/214 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 MRMFFIFF-GAGLIVFLCVPFMILRPRDYRNALFPSW-----CFRQLCRLV-------GITMEVR 79
            :|..|:|. ....|...|:..::|:|....:|. ..|     .||.|..:|       |.|:...
Zfish    20 LRFTFMFVNNCVAIPSYCLYLIVLQPLRVLDAQ-TFWYIEGVMFRWLLAMVASWGWCAGYTVTEW 83

  Fly    80 G--LENVRKDHGAVVIMNHQSAVDLCVLAYLWPVIGRATVVSK-----KEVLYIPFFGIGAWLWG 137
            |  :..:.:|. |:||:|||:..|:|.|  :..:..:.|||.|     ..|.....||:.:.:.|
Zfish    84 GDDVSPMTEDE-AMVIVNHQATGDVCTL--MMCLQDKGTVVRKMMWLMDHVFKYTNFGVVSLIHG 145

  Fly   138 TLYIDRS---RKTDSINSLQKEAKAIQERNCK-LLLFPEG--------TRNS--KDSLLPF---- 184
            ..:|.:.   |:...:.......|....|:.| ::|||||        |..|  |.:.||:
Zfish   146 DFFIRQGKAHREKQLVYLKDHLDKFYYSRDRKWIVLFPEGGFLRKRRETSQSFAKKNDLPYLTHV 210

  Fly   185 ---KKGSFHIALQGKSPVQ 200
               :.|:..|.|:...|.|
Zfish   211 TLPRLGATQIILKNLGPQQ 229

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat2	NP_001162912.1	LPLAT_AGPAT-like	65..248	CDD:153251	45/171 (26%)
lpgat1	NP_001025129.1	LPLAT_LCLAT1-like	69..286	CDD:153252	42/164 (26%)
lpgat1	NP_001025129.1	Acyltransf_C	275..>331	CDD:292694
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810