Protein Alignment Agpat2 and LPCAT2

DIOPT Version :10

• Sequence 1: NP_609231.2
• Gene: Agpat2 / 34176
• FlyBaseID: FBgn0026718
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_060309.2
• Gene: LPCAT2 / 54947
• HGNCID: 26032
• Length: 544
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 70/325 - (21%)
• Similarity: 124/325 - (38%)
• Gaps: 93/325 - (28%)

  Fly     8 IGLACVVALILSATAKAPYQMRMFFIFFGAGLIVFLCVPFMIL----------------RPRDYR 56
            ||.|..|.::|......|.::.:      ..||:.|..||..:                |.:..:
Human    50 IGSARRVQIVLLGIILLPIRVLL------VALILLLAWPFAAISTVCCPEKLTHPITGWRRKITQ 108

  Fly    57 NALFPSWCFRQLCRLVGITMEVRGLENVRKDHGAVVIMNHQSAVD--LCVLAYLWPVIGRATVVS 119
            .||  .:..|.:...:|..:.|:|......:....|...|.:..|  .||:|      |..::||
Human   109 TAL--KFLGRAMFFSMGFIVAVKGKIASPLEAPVFVAAPHSTFFDGIACVVA------GLPSMVS 165

  Fly   120 KKEVLYIPFFGIGAWLWG-----TLYIDRSRKTDSINSLQKEAKAIQERNCKLLLFPEGTRNSKD 179
            :.|...:|.  ||..|..     ...:|...:.::||.:.|...:..|.. ::|:|||||..::.
Human   166 RNENAQVPL--IGRLLRAVQPVLVSRVDPDSRKNTINEIIKRTTSGGEWP-QILVFPEGTCTNRS 227

  Fly   180 SLLPFKKGSFHIALQGKSPVQPVVISKYSFMDDEKKTFRPGHALIHI----------------LP 228
            .|:.||.|:|   :.| .|||||::...:.:|....|:: |:..|.:                :|
Human   228 CLITFKPGAF---IPG-VPVQPVLLRYPNKLDTVTWTWQ-GYTFIQLCMLTFCQLFTKVEVEFMP 287

  Fly   229 -EVSTEKYKR--------------------------EDVQLLIDECQSIMQ-----TEYTKLSKE 261
             :|..::.|.                          ||.:|:|...|..:.     .|:||:|::
Human   288 VQVPNDEEKNDPVLFANKVRNLMAEALGIPVTDHTYEDCRLMISAGQLTLPMEAGLVEFTKISRK 352

  Fly   262  261
            Human   353  352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Agpat2	NP_609231.2	PlsC	47..261	CDD:439974	60/284 (21%)
LPCAT2	NP_060309.2	LPLAT_LPCAT1-like	116..327	CDD:153253	49/224 (22%)
		HXXXXD motif. /evidence=ECO:0000250|UniProtKB:Q3TFD2	146..151		1/4 (25%)
		EGTC motif	220..223		2/2 (100%)
		FRQ1	377..489	CDD:444056
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	518..544