DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Agpat2 and Lpcat1

DIOPT Version :9

Sequence 1:	NP_001162912.1	Gene:	Agpat2 / 34176	FlyBaseID:	FBgn0026718	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_001094205.1	Gene:	Lpcat1 / 361467	RGDID:	1311599	Length:	534	Species:	Rattus norvegicus

Alignment Length:	298	Identity:	75/298 - (25%)
Similarity:	124/298 - (41%)	Gaps:	80/298 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LILSATAKAP--------YQMRMFFIFFGAGLIVFLCVPFMI---LRPRDYRNALFPSWCFRQ-- 67
            |.|||..||.        :.:|:.|    |..::.|..||.:   |.|.| :....|...:|:
  Rat    36 LRLSALQKAQVAFMTLTLFPIRLLF----AAFMMLLAWPFALVASLGPPD-KEPEQPLALWRKVV 95

  Fly    68 --LCRLVGITM---------EVRGLENVRKDHGAVVIMNHQSAVDLCVLAYLWPV-IGRATVVSK 120
              |.:.:..||         .|:|.:.:..:...:.:..|.|..|..      || :..:::|.|
  Rat    96 DFLLKAIMRTMWFAGGFHRVAVKGRQALPTEAAILTLAPHSSYFDAI------PVTMTMSSIVMK 154

  Fly   121 KEVLYIPFFGIGAWLWGTL-------YIDRSRKTDSINSLQKEAKAIQERNCK---LLLFPEGTR 175
            .|...||       :||||       ::.||.: ||.....:|.|...:.|.|   :::|||||.
  Rat   155 AESRDIP-------IWGTLIRYIRPVFVSRSDQ-DSRRKTVEEIKRRAQSNGKWPQIMIFPEGTC 211

  Fly   176 NSKDSLLPFKKGSFHIALQGKSPVQPVVISKYSFMDDEKKTFRPGHAL---------------IH 225
            .::..|:.||.|:|   :.| .||||||:...:.:|....|::...||               |.
  Rat   212 TNRTCLITFKPGAF---IPG-VPVQPVVLRYPNKLDTITWTWQGPGALKILWLTLCQFQNQVEIE 272

  Fly   226 ILP-EVSTEKYKR------EDVQLLIDECQSIMQTEYT 256
            .|| ...:|:.||      .:|:.::.:...:..|:||
  Rat   273 FLPVYCPSEEEKRNPALYASNVRRVMAKALGVSVTDYT 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat2	NP_001162912.1	LPLAT_AGPAT-like	65..248	CDD:153251	56/228 (25%)
Lpcat1	NP_001094205.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..25
		PlsC	59..>242	CDD:223282	54/205 (26%)
		LPLAT_LPCAT1-like	103..314	CDD:153253	57/226 (25%)
		HXXXXD motif. /evidence=ECO:0000250\|UniProtKB:Q3TFD2	135..140		2/4 (50%)
		EFh	<350..412	CDD:298682
		EFh	384..446	CDD:298682
		EF-hand_7	421..479	CDD:290234
		EF-hand_8	432..483	CDD:290545
		Di-lysine motif. /evidence=ECO:0000250\|UniProtKB:Q3TFD2	531..534
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810