Protein Alignment Agpat2 and LCLAT1

DIOPT Version :10

• Sequence 1: NP_609231.2
• Gene: Agpat2 / 34176
• FlyBaseID: FBgn0026718
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_872357.2
• Gene: LCLAT1 / 253558
• HGNCID: 26756
• Length: 414
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 66/271 - (24%)
• Similarity: 108/271 - (39%)
• Gaps: 71/271 - (26%)

  Fly    30 MFFI-------FFGAGLIVFLCVPFMILRPRDYR---NALFPSWCFRQLCRL---VGITMEVRGL 81
            ::||       |||:..::...:|.|.:.|..||   |.|..:|....:..|   .|:.:.:.|.
Human    45 IYFILTLFWGSFFGSIFMLSPFLPLMFVNPSWYRWINNRLVATWLTLPVALLETMFGVKVIITGD 109

  Fly    82 ENVRKDHGAVVIMNHQSAVDLCVLAYLWPVIGRAT------VVSKKEVLYIPFFGIGAW-LWGTL 139
            ..|..:. :|:||||::.:|   ..:||..:.|.:      :..|..:..:|.||   | :....
Human   110 AFVPGER-SVIIMNHRTRMD---WMFLWNCLMRYSYLRLEKICLKASLKGVPGFG---WAMQAAA 167

  Fly   140 YI--------DRSRKTDSINSLQKEAKAIQERNCKLLLFPEG---TRNSKDSLLPF--KKG--SF 189
            ||        |:|...|.|:......:.:|     ||:||||   |.|||.....|  |.|  .:
Human   168 YIFIHRKWKDDKSHFEDMIDYFCDIHEPLQ-----LLIFPEGTDLTENSKSRSNAFAEKNGLQKY 227

  Fly   190 HIAL---------------QGKS--PVQPVVIS-KYSFMDDEKKTF-----RPGHALIHILPEVS 231
            ...|               :||:  .|..:.:: .::....||...     |..|..:|..| :.
Human   228 EYVLHPRTTGFTFVVDRLREGKNLDAVHDITVAYPHNIPQSEKHLLQGDFPREIHFHVHRYP-ID 291

  Fly   232 TEKYKREDVQL 242
            |....:||:||
Human   292 TLPTSKEDLQL 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Agpat2	NP_609231.2	PlsC	47..261	CDD:439974	60/247 (24%)
LCLAT1	NP_872357.2	LPLAT_LCLAT1-like	93..286	CDD:153252	46/204 (23%)
		HXXXXD motif. /evidence=ECO:0000250|UniProtKB:Q9D517	123..128		1/4 (25%)
		Acyltransf_C	271..345	CDD:465006	9/33 (27%)