Protein Alignment Agpat2 and Lpcat1

DIOPT Version :10

• Sequence 1: NP_609231.2
• Gene: Agpat2 / 34176
• FlyBaseID: FBgn0026718
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_663351.3
• Gene: Lpcat1 / 210992
• MGIID: 2384812
• Length: 534
• Species: Mus musculus
• Alignment Length: 298
• Identity: 75/298 - (25%)
• Similarity: 124/298 - (41%)
• Gaps: 80/298 - (26%)

  Fly    16 LILSATAKAP--------YQMRMFFIFFGAGLIVFLCVPFMILR---PRDYRNALFPSWCFRQ-- 67
            |.|||..||.        :.:|:.|    |..::.|..||.:|.   |.| :....|...:|:
Mouse    36 LRLSALQKAQVAFMTLTLFPIRLLF----AAFMMLLAWPFALLASLGPPD-KEPEQPLALWRKVV 95

  Fly    68 --LCRLVGITM---------EVRGLENVRKDHGAVVIMNHQSAVDLCVLAYLWPV-IGRATVVSK 120
              |.:.:..||         .|:|.:.:..:...:.:..|.|..|..      || :..:::|.|
Mouse    96 DFLLKAIMRTMWFAGGFHRVAVKGRQALPTEAAILTLAPHSSYFDAI------PVTMTMSSIVMK 154

  Fly   121 KEVLYIPFFGIGAWLWGTL-------YIDRSRKTDSINSLQKEAKAIQERNCK---LLLFPEGTR 175
            .|...||       :||||       ::.||.: ||.....:|.|...:.|.|   :::|||||.
Mouse   155 AESRDIP-------IWGTLIRYIRPVFVSRSDQ-DSRRKTVEEIKRRAQSNGKWPQIMIFPEGTC 211

  Fly   176 NSKDSLLPFKKGSFHIALQGKSPVQPVVISKYSFMDDEKKTFRPGHAL---------------IH 225
            .::..|:.||.|:|   :.| .||||||:...:.:|....|::...||               |.
Mouse   212 TNRTCLITFKPGAF---IPG-VPVQPVVLRYPNKLDTITWTWQGPGALKILWLTLCQFQNQVEIE 272

  Fly   226 ILP-EVSTEKYKR------EDVQLLIDECQSIMQTEYT 256
            .|| ...:|:.||      .:|:.::.:...:..|:||
Mouse   273 FLPVYCPSEEEKRNPALYASNVRRVMAKALGVSVTDYT 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Agpat2	NP_609231.2	PlsC	47..261	CDD:439974	64/259 (25%)
Lpcat1	NP_663351.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25
		LPLAT_LPCAT1-like	103..314	CDD:153253	57/226 (25%)
		HXXXXD motif. /evidence=ECO:0000269|PubMed:18285344	135..140		2/4 (50%)
		EFh	<350..412	CDD:415501
		FRQ1	<384..494	CDD:444056
		EF-hand_8	432..483	CDD:404678
		Di-lysine motif. /evidence=ECO:0000305|PubMed:16704971	531..534