Protein Alignment Agpat2 and GPAT4

DIOPT Version :10

• Sequence 1: NP_609231.2
• Gene: Agpat2 / 34176
• FlyBaseID: FBgn0026718
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_848934.1
• Gene: GPAT4 / 137964
• HGNCID: 20880
• Length: 456
• Species: Homo sapiens
• Alignment Length: 213
• Identity: 50/213 - (23%)
• Similarity: 85/213 - (39%)
• Gaps: 60/213 - (28%)

  Fly    33 IFFGAGLIVFLC--VPFMIL----------------------RPRDYRNALFPSWCFRQLCRLVG 73
            :.:|.|:::..|  :|..|.                      |.:::.:......|:|...|.:.
Human   162 VLWGLGVLIRYCFLLPLRIALAFTGISLLVVGTTVVGYLPNGRFKEFMSKHVHLMCYRICVRALT 226

  Fly    74 ITMEVRGLENVRKDHGAVVIMNHQSAVDLCVLAY-------------LWPVIGRATVVSKKEVLY 125
            ..:.....|| |..:|.:.:.||.|.:|:.:||.             |..||.||.|.:...|
Human   227 AIITYHDREN-RPRNGGICVANHTSPIDVIILASDGYYAMVGQVHGGLMGVIQRAMVKACPHV-- 288

  Fly   126 IPFFGIGAWLWGTLYIDRSRKTDSINSLQKEAKAIQERN-CKLLLFPEGTRNSKDSLLPFKKGSF 189
                          :.:||...|.....::..:.:|::: ..:|:|||||..:..|::.||||||
Human   289 --------------WFERSEVKDRHLVAKRLTEHVQDKSKLPILIFPEGTCINNTSVMMFKKGSF 339

  Fly   190 HIALQGKSPVQPVVISKY 207
            .|.    :.|.||.| ||
Human   340 EIG----ATVYPVAI-KY 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Agpat2	NP_609231.2	PlsC	47..261	CDD:439974	46/197 (23%)
GPAT4	NP_848934.1	LPLAT_LPCAT1-like	218..427	CDD:153253	43/157 (27%)
		HXXXXD motif. /evidence=ECO:0000250|UniProtKB:Q9D517	248..253		2/4 (50%)