Protein Alignment Agpat2 and TMEM68

DIOPT Version :10

• Sequence 1: NP_609231.2
• Gene: Agpat2 / 34176
• FlyBaseID: FBgn0026718
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_001273586.1
• Gene: TMEM68 / 137695
• HGNCID: 26510
• Length: 324
• Species: Homo sapiens
• Alignment Length: 219
• Identity: 45/219 - (20%)
• Similarity: 81/219 - (36%)
• Gaps: 63/219 - (28%)

  Fly    77 EVRGLENVRKDHGAVVIMNHQSAVDLCVLAYLWPVI---GR-ATVVSKKEVLYIPFFGIGAWLWG 137
            ||.|:|.:.:|..|::|..| .|:.:....::..:.   || ..||:...|..||.|.:...::.
Human   111 EVHGMEKIPEDGPALIIFYH-GAIPIDFYYFMAKIFIHKGRTCRVVADHFVFKIPGFSLLLDVFC 174

  Fly   138 TLYIDRSRKTDSINSLQKEAKAIQERNCKLLLFPEGTRNSKDS------LLPFKKGSFHIALQGK 196
            .|:..|.:..:.:.|           ...|.:.|.|.|.:..|      :...::|...:|:..|
Human   175 ALHGPREKCVEILRS-----------GHLLAISPGGVREALISDETYNIVWGHRRGFAQVAIDAK 228

  Fly   197 SPVQPVVISKYSFMDDEKKTFRP--GHALIHIL------------------------------PE 229
            .|:.|:      |..:.::.||.  |..|...|                              |:
Human   229 VPIIPM------FTQNIREGFRSLGGTRLFRWLYEKFRYPFAPMYGGFPVKLRTYLGDPIPYDPQ 287

  Fly   230 VSTEKY---KREDVQLLIDECQSI 250
            ::.|:.   .:..||.|||:.|.|
Human   288 ITAEELAEKTKNAVQALIDKHQRI 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Agpat2	NP_609231.2	PlsC	47..261	CDD:439974	45/219 (21%)
TMEM68	NP_001273586.1	LPLAT_MGAT-like	103..310	CDD:153249	43/216 (20%)