DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Agpat2 and Aup1

DIOPT Version :9

Sequence 1:	NP_001162912.1	Gene:	Agpat2 / 34176	FlyBaseID:	FBgn0026718	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_031543.3	Gene:	Aup1 / 11993	MGIID:	107789	Length:	410	Species:	Mus musculus

Alignment Length:	278	Identity:	68/278 - (24%)
Similarity:	111/278 - (39%)	Gaps:	53/278 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LILSATAKAPYQMRMFFIFFGAGLIVFL---CVPFMILRPRDYRNALFPSWCFRQLCRLVGIT-- 75
            |:|:....||..:.:..:....||.|||   .:|..:||          .:..|.:|.::|:.
Mouse    24 LLLALLLYAPVGLCLLVLRLFLGLHVFLVSCALPDSVLR----------RFVVRTMCAVLGLVAR 78

  Fly    76 MEVRGLENVRKDHGA-VVIMNHQSAVDLCVLAYLWPVIGRATVVSKKEVLYIPFFGIGAWLWGTL 139
            .|..||    :||.. |:|.||.:..|       ..::...|..|...:...|.|    ..|...
Mouse    79 QEDSGL----RDHRVRVLISNHVTPFD-------HNIVNLLTTCSTPLLNSPPSF----VCWSRG 128

  Fly   140 YIDRSRKTDSINSLQKEAKAIQERNCKLLLFP-EGTRNSKDSLLPFKKGSFHI-------ALQGK 196
            :::..|:.:.:.||:|...:.:.....||||| |...|.::.||.|....|.|       .||.:
Mouse   129 FMEMDRRVELVESLKKFCASTRLPPTPLLLFPEEEATNGREGLLRFSSWPFSIQDVVQPLTLQVQ 193

  Fly   197 SPVQPVVISKYSFMDDEK-KTFRPG--------HALIHILPEVSTEKYKREDVQLLIDECQSIMQ 252
            .|:..|.:|..|::.:.. ..|.|.        |.:...|.|.| |::.....||:..|...|
Mouse   194 RPLVSVTVSDASWVSELLWSLFVPFTVYQVRWLHPIRRQLGEES-EEFALRVQQLVAKELGQI-- 255

  Fly   253 TEYTKLSKEGQALSSKKQ 270
              .|:|:...:|...|:|
Mouse   256 --GTRLTPADKAEHMKRQ 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat2	NP_001162912.1	LPLAT_AGPAT-like	65..248	CDD:153251	50/202 (25%)
Aup1	NP_031543.3	LPLAT	66..264	CDD:418432	53/217 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	258..295		4/14 (29%)
		CUE_AUP1	296..340	CDD:270603
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	344..369
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900