DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Agpat2 and AGPAT1

DIOPT Version :9

Sequence 1:	NP_001162912.1	Gene:	Agpat2 / 34176	FlyBaseID:	FBgn0026718	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_001358366.1	Gene:	AGPAT1 / 10554	HGNCID:	324	Length:	287	Species:	Homo sapiens

Alignment Length:	244	Identity:	82/244 - (33%)
Similarity:	135/244 - (55%)	Gaps:	6/244 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 APYQMRMFFIFFGAGLIVFLCV---PFMILRPRDYRNALFPSWCFRQLCRLVGITMEVRGLENVR 85
            :|.....|.:.|..|.|:||.|   |...:|.|:..|..........:..|.||.:||||..:..
Human    33 SPSAKYFFKMAFYNGWILFLAVLAIPVCAVRGRNVENMKILRLMLLHIKYLYGIRVEVRGAHHFP 97

  Fly    86 KDHGAVVIMNHQSAVDLCVLAYLWPVIGRATVVSKKEVLYIPFFGIGAWLWGTLYIDRSRKTDSI 150
            .....||:.||||::||..:..:.|  ||...::|:|:|:....|:..||.|.::|||.|..|:|
Human    98 PSQPYVVVSNHQSSLDLLGMMEVLP--GRCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAI 160

  Fly   151 NSLQKEAKAIQERNCKLLLFPEGTRNSKDSLLPFKKGSFHIALQGKSPVQPVVISKY-SFMDDEK 214
            :.:.:.|:.:..::.::.:|||||||...|:||||:|:||:|:|.:.|:.|:|:|.| .|...::
Human   161 SVMSEVAQTLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYCKKE 225

  Fly   215 KTFRPGHALIHILPEVSTEKYKREDVQLLIDECQSIMQTEYTKLSKEGQ 263
            :.|..|...:.:||.|.||....:||..|.|..:..|.|.:.::|.:|:
Human   226 RRFTSGQCQVRVLPPVPTEGLTPDDVPALADRVRHSMLTVFREISTDGR 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat2	NP_001162912.1	LPLAT_AGPAT-like	65..248	CDD:153251	66/183 (36%)
AGPAT1	NP_001358366.1	LPLAT_AGPAT-like	73..259	CDD:153251	66/187 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141865
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1623097at2759
OrthoFinder	1	1.000	-	-		FOG0001236
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100535
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X864
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.710