DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Agpat2 and Lpcat2

DIOPT Version :9

Sequence 1:	NP_001162912.1	Gene:	Agpat2 / 34176	FlyBaseID:	FBgn0026718	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_001258273.1	Gene:	Lpcat2 / 100359680	RGDID:	2325051	Length:	544	Species:	Rattus norvegicus

Alignment Length:	261	Identity:	64/261 - (24%)
Similarity:	115/261 - (44%)	Gaps:	54/261 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 GLIVFLCVPFMILR----PR-------DYRNALF-PSWCF--RQLCRLVGITMEVRGLENVRKDH 88
            ||::.|..||.::.    |:       |:|..:. |:..|  |.:...:|..:.|:|......:.
  Rat    74 GLVLLLAWPFAVISTVCCPKKLTHPISDWRRKITQPALKFLGRAMFFSMGFRVTVKGKVASPLEA 138

  Fly    89 GAVVIMNHQSAVD--LCVLAYLWPVIGRATVVSKKEVLYIPFFG-IGAWLWGTLY--IDRSRKTD 148
            ...|:..|.:..|  .||:|      |..::||:.|....|..| :...|...|.  :|...:.:
  Rat   139 PIFVVAPHSTFFDGIACVVA------GLPSLVSRNENAQTPLVGRLLRALQPVLVSRVDPDSRKN 197

  Fly   149 SINSLQKEAKAIQERNCKLLLFPEGTRNSKDSLLPFKKGSFHIALQGKSPVQPVVISKYSFMDDE 213
            :||.::|.|.:..|.. ::|:|||||..::..|:.||.|:|   :.| .|||||::...:.:|..
  Rat   198 TINEIKKRAMSGGEWP-QILVFPEGTCTNRSCLITFKPGAF---IPG-VPVQPVLLRYPNKLDTV 257

  Fly   214 KKTFRPGHALIHI----------------LPEVSTEKYKRED-------VQLLIDECQSIMQTEY 255
            ..|:: |:..|.:                :|..:..:.:|.|       |:.|:.|...|..|::
  Rat   258 TWTWQ-GYTFIQLCVLTFCQLFTKVEVEFMPVQAPSEEERNDPVLFASRVRNLMAEALEIPVTDH 321

  Fly   256 T 256
            |
  Rat   322 T 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat2	NP_001162912.1	LPLAT_AGPAT-like	65..248	CDD:153251	52/212 (25%)
Lpcat2	NP_001258273.1	PlsC	103..>254	CDD:223282	44/161 (27%)
		LPLAT_LPCAT1-like	116..327	CDD:153253	54/219 (25%)
		HXXXXD motif. /evidence=ECO:0000250\|UniProtKB:Q3TFD2	146..151		1/4 (25%)
		EGTC motif	220..223		2/2 (100%)
		EFh	396..458	CDD:238008
		EF-hand_7	396..457	CDD:290234
		EF-hand_7	433..489	CDD:290234
		EFh	433..486	CDD:238008
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	520..544
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810