Protein Alignment Aasdh and Aasdh

DIOPT Version :10

• Sequence 1: NP_609230.2
• Gene: Aasdh / 34175
• FlyBaseID: FBgn0027780
• Length: 1012
• Species: Drosophila melanogaster
• Sequence 2: NP_001385951.1
• Gene: Aasdh / 364136
• RGDID: 1311135
• Length: 1099
• Species: Rattus norvegicus
• Alignment Length: 1128
• Identity: 303/1128 - (26%)
• Similarity: 483/1128 - (42%)
• Gaps: 271/1128 - (24%)

  Fly    61 LRKNGVPDEAGIALRVTEHTPASSLMILAILNNKCHFFPTDKMMLSQDLYSQMSTAGVDYLVANK 125
            :|:.|:..:.||.|      |:   .||.||.....:.|.|...|.......|...|:.|::..|
  Rat    58 IREIGLYCQPGINL------PS---WILGILQIPAAYAPIDPDSLPSLATHFMKKCGLKYVLVEK 113

  Fly   126 ---------HLTVAPLYFTF------------------LGSILVFKEDCRLYRVKLKSADETV-- 161
                     |.||.. |.|.                  :.|:|..:.|    :.|:...:|.|
  Rat   114 RQITKFKSSHETVLN-YDTVSVEHKDLVLLRLHWEDGAVNSVLSDRTD----KCKVNDREERVNG 173

  Fly   162 ----QSKKPLPAN----MCYTISTTGTTGKPKLIHVPYECIAPNIVGLSQKLNVSMADIIYLGTP 218
                |.|..:...    :.|.:.|:||||.||::.||:.||.|||.......:::..|:::|.:|
  Rat   174 ENGSQEKGHMDMRREGCLAYVLHTSGTTGTPKIVRVPHACILPNIQHFRSLFDITQEDVLFLASP 238

  Fly   219 ITFDPFVVEFFLALQNGATLLTSRHSMRDSPSKVLSALFPDNLATPGITVLQMTPSLFRQFGASS 283
            :||||.|||.|:||.:||.||.|..|::..|||:...||    :...:||||.||:|.|:||:..
  Rat   239 LTFDPSVVEIFVALSSGACLLISPTSVKVLPSKLADVLF----SRHRVTVLQATPTLLRRFGSEL 299

  Fly   284 IKDRVLSGSSSLRVLLLGGEPFPSNVELVTWMHPSVLMQKHICNIYGITEISCWSLLH-----IV 343
            :|..|||..:|||||.||||.|||...|.:|...|...|  |.|||||||:|.|:..:     |:
  Rat   300 MKSTVLSAHTSLRVLALGGEAFPSLTVLQSWRGKSNRTQ--IFNIYGITEVSSWATFYRIPEEIL 362

  Fly   344 QS---LQSPVPLGTPIEEDTVLRIESEDNETSQQ--GELFLGSVKRRCYIPEVDDQANASQDDSG 403
            .|   |:|||.||:|: ..||:.:..::.....:  |::|||...|.|::   |::......
  Rat   363 NSSVRLESPVQLGSPL-LGTVVEVRDKNGSPVHEGTGQVFLGGKNRICFL---DEEMTVPLG--- 420

  Fly   404 ICFRATGDLVTRQQDGTLFYSERSNDVVKRAGNRISLGLITRKIQKCLPSSELTTCLWLEDLQKL 468
             ..|||||.|| .:.|.:|:..|.:..:||.|.|:|:.|:.:.               .|:|:::
  Rat   421 -TMRATGDFVT-VKGGEIFFLGRKDSQIKRHGKRLSIALVQQV---------------AEELRQV 468

  Fly   469 ICCIRTLESKTRVQQRVQTFDILSKVSIAEQ---------------PDRFVYLQHFPCNVHGKLD 518
            ..|..|..:    |:::..| |:|||.:.:.               ||..|.:...|...|||:|
  Rat   469 ESCAVTWYN----QEKLILF-IVSKVDLVKDYIFKELQKHLPAHALPDDMVLIGSLPVTCHGKVD 528

  Fly   519 KQQLLKMCIPL--AQPAQQIL-KSYLHDRLECVEE-----PDDSASKKQRLDDAAPCGYDLSFRQ 575
            ..:|.|:.:..  :||..::. |..|..:|:|:.:     |:|...|..  |::.       |..
  Rat   529 VSELNKIYLDYISSQPRNKLHGKEELWGKLQCLWKSILCLPEDPELKVP--DNSV-------FLD 584

  Fly   576 AGGTSFHAITICREIG----------LQMCID----DEQRHLFEMLLD-ENIP----LRTVLRFL 621
            :||.|..::.:..|:.          |::.:.    |...|:.:.:|. |::.    ..|..:|.
  Rat   585 SGGDSLKSLWLLGEVEKLTGAPVPGLLEVILSSSFLDVYNHIIQAVLTREDLKGDRRYTTKRKFS 649

  Fly   622 D---------TAKLVANNIKRKNVETAVVVS--------------------ACQSGL-------- 649
            |         .|:|.|.....::.||..||:                    .|.:.:
  Rat   650 DPDSEETSGKPARLEAAWPWHRDSETNSVVALSRGSQTLYLGTGRLLTELGLCPNAVHPPDLIPQ 714

  Fly   650 ----IIKRIEQPVLK----------------------LQIYWKVNFEKCID-SP------VTEYE 681
                |:|.:..|.|.                      |:..|:.:..||:| ||      |.:..
  Rat   715 TNTEILKSLSPPALDETLEKPPLSQERSPGTGAEPMVLRERWRSDTGKCVDASPLLVVAAVGDTS 779

  Fly   682 GRFICVGAHSKILRTLNPQTGSEYSVVKLPERIECKV------TFLTEQLAMVGCYDGCLYGFNP 740
            ...:.:|:||..::.::..:|......::.:|||...      .|:     :||||||.:|....
  Rat   780 STTVYIGSHSHTVKAVDLHSGEMRWERRVGDRIESSACVSKCGNFI-----VVGCYDGLVYVLKS 839

  Fly   741 QTGNIVFRVGIGGLIKSQPMLTADGRRIIVCSYADDYNVYCLSAERQEVLWCLRIGEKPIFASPL 805
            .:|...:.......:||.|.:......|.|.|:  |.:.|.|....::.:|.|:. |..:|:||.
  Rat   840 NSGEKHWTFPTEDAVKSSPAVDPTTGLIYVGSH--DQHAYALDIYEKKCVWKLKC-EGALFSSPC 901

  Fly   806 ELPREQSLIVCTLDGSYSRVAITDGSVEWTQKFREPVFSTP------VLLESVSNIFLSAEVAGR 864
            .......|...||.|....|....||:.|.:...:|:||:|      |.:..|....|
  Rat   902 LSLGPHHLYCATLGGLLLAVNPATGSLIWKRPCGKPLFSSPRCYQHYVCIGCVDGSLL------- 959

  Fly   865 VHACHVGNGKILATFSTEGNIFSSLVVKTPPTFMGHSFAIFGCIDQHLYCLRCKTGPGGKSVELE 929
               |...:|:.:..||..|.||||     |..........||..|..|||  |.|..|
  Rat   960 ---CFSHSGEQVWRFSAGGPIFSS-----PCISASEQDIYFGSHDCFLYC--CSTEGG------- 1007

  Fly   930 LHWKVDVGAPIYATPTLLTVQPN-----GLLVWCAATDGRVMLINFRNGEIQWSDKLPGQVFSSA 989
            |.||.:..|.:|:||...   ||     |.|:..|:|||::.::..::||::...:|||:||||.
  Rat  1008 LRWKFETTARVYSTPFAF---PNHLCGSGTLLAAASTDGKLWVLESQSGELRSVYELPGEVFSSP 1069

  Fly   990 CFIEDLRRVFVGCRDNFLYCLGI 1012
            ...|.:  :.:|||:|::|||.:
  Rat  1070 VVWESM--LVIGCRNNYIYCLDL 1090

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aasdh	NP_609230.2	A_NRPS_acs4	29..522	CDD:341309	161/522 (31%)
		PQQ	656..>791	CDD:441129	35/169 (21%)
		PQQ_2	732..978	CDD:433144	70/256 (27%)
		PQQ_3	973..1010	CDD:463925	15/36 (42%)
Aasdh	NP_001385951.1	A_NRPS_acs4	16..532	CDD:341309	165/537 (31%)
		WD40 repeat	751..786	CDD:293791	9/34 (26%)
		PQQ_2	791..1011	CDD:433144	70/230 (30%)
		WD40 repeat	793..847	CDD:293791	17/59 (29%)
		WD40 repeat	854..898	CDD:293791	11/43 (26%)
		WD40 repeat	906..932	CDD:293791	10/25 (40%)
		PQQ	<964..>1079	CDD:441129	17/46 (37%)