DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Aasdh and CG12512

DIOPT Version :9

Sequence 1:	NP_609230.2	Gene:	Aasdh / 34175	FlyBaseID:	FBgn0027780	Length:	1012	Species:	Drosophila melanogaster
Sequence 2:	NP_608924.1	Gene:	CG12512 / 33766	FlyBaseID:	FBgn0031703	Length:	593	Species:	Drosophila melanogaster

Alignment Length:	573	Identity:	121/573 - (21%)
Similarity:	198/573 - (34%)	Gaps:	129/573 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 FKDVPFLIRRTESKDTIVSYADAADEIQVLMNFLRKNGVPDEAGIALRVTEH------------- 79
            |.||..::...|.|.  .|:.....|...|....||.|:.....:.|....:
  Fly    60 FGDVEAIVSCHEGKR--YSFKSLLQEADALAAGFRKLGLQPGDAVGLWAPNYLHWYLGMMGAARA 122

  Fly    80 -------TPASSLMILAILNNKCHF--------FPTDKMM-LSQDLYSQMSTAGVDYLVANKHLT 128
                   .||.....:|...||.:.        |.|.... :.:|:..::|.|....:.:.|
  Fly   123 GLTSVGLNPAYQGPEIAYCLNKVNVKAIIAPETFKTQNYYEILRDICPEISDADTGKIRSEK--- 184

  Fly   129 VAPLYFTFLGSILVFKEDCRLYRVKL--------KSADETV--QSKKPLPANMCYTISTTGTTGK 183
                 |..|.|:::...|.....::.        ||..|.|  ..|..||.:.|....|:||||.
  Fly   185 -----FPHLRSVIIDSNDSLKGALRFDDFLDLASKSEREEVAKMQKSILPESACNIQFTSGTTGN 244

  Fly   184 PKLIHVPYECIAPNIVGLSQKLNVSMADIIYLGTPITFDPF--VVEFFLALQNGATLLTSRHSMR 246
            ||...:.:.....|.:.:..: |....:.|.:..|: |..|  ::....||..|||::......
  Fly   245 PKAACLTHHNFVNNGIHVGNR-NELEGERICVQVPM-FHAFGVIISIMAALTKGATMVLPAAGF- 306

  Fly   247 DSPSKVLSALFPDNLATPGITVLQMTPSLF---------RQFGASSIKDRVLSGS-------SSL 295
             ||...|.|:..:.     .:|:..||:::         .|.....||..|..|:       ..:
  Fly   307 -SPKDSLQAIVNEK-----CSVIHGTPTMYVDLVNTQKKLQVPLGRIKKAVTGGAIVSPQLIKDV 365

  Fly   296 RVLLLGGEPFPSNVELVTWMHPSVLMQKHICNIYGITEISCWSLLHIVQSL---QSPVPLG---- 353
            |.:|        |||.|           |  ::||:||.:.    .|.|||   .|.|.|.
  Fly   366 RQVL--------NVEAV-----------H--SVYGLTETTA----VIFQSLPGDSSDVVLNSVGH 405

  Fly   354 -TPIEEDTVLRIESEDNETSQQGELFLGSVKRRCYIPEV---DDQANASQDDSGICFRATGDLVT 414
             |...|..|:..|.......|.|||.:     |.|...:   ||:....:......:..|||...
  Fly   406 LTDHIEAKVVDAEGRCVPFGQPGELCV-----RGYTTMLGYHDDEEKTKETIGNDRWLRTGDQFV 465

  Fly   415 RQQDGTLFYSERSNDVVKRAGNRISLGLITRKIQKCL---PSSELTTCLWLED--LQKLICC-IR 473
            .:.:|......|..:::.|.|..|    ..::|:..|   |.......:.:.|  |.:.:|. :|
  Fly   466 LEANGYGRIVGRLKEMLIRGGENI----FPKEIEDFLNAHPQVIEAHVIGVPDERLGEEVCAYVR 526

  Fly   474 TLESKTRVQQRVQTFDILSKVSIA--EQPDRFVYLQHFPCNVHGKLDKQQLLK 524
            ..|.........:|....:|..:|  :.|...:.:..||....||:.|.:|::
  Fly   527 LEEGVDPASFTAETLKAYAKGKLAHFKVPRYVIPIDAFPKTTSGKIQKFKLVE 579

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Aasdh	NP_609230.2	AA-adenyl-dom	46..443	CDD:273779	98/464 (21%)
		AFD_class_I	<168..522	CDD:302604	87/390 (22%)
		PQQ_DH_like	<728..1012	CDD:299747
		PQQ_2	732..978	CDD:290097
CG12512	NP_608924.1	PRK08315	43..592	CDD:236236	121/573 (21%)
CG12512	NP_608924.1	FACL_like_2	229..577	CDD:213284	87/390 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456986
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840