Protein Alignment Aasdh and W09D6.1

DIOPT Version :9

• Sequence 1: NP_609230.2
• Gene: Aasdh / 34175
• FlyBaseID: FBgn0027780
• Length: 1012
• Species: Drosophila melanogaster
• Sequence 2: NP_001255106.1
• Gene: W09D6.1 / 176537
• WormBaseID: WBGene00012356
• Length: 889
• Species: Caenorhabditis elegans
• Alignment Length: 990
• Identity: 230/990 - (23%)
• Similarity: 394/990 - (39%)
• Gaps: 220/990 - (22%)

  Fly    92 NNKCHFFPTDKMMLSQDLYSQMSTAGVDYLVANKHLTVAPLYFTFLGSILVFKEDCRLYRVKL-- 154
            |:.|      :.:...|:.......|:|.:||........|.|||........:..|.:|..|
 Worm    37 NSNC------RAITGSDVVFISIERGLDAIVAVIACLRLELVFTFCPPASDTDDVVRKFRTTLVF 95

  Fly   155 --KSADETVQSKKP--LPA-NMCYTISTTGTTGKPKLIHVPYECIAPNIVGLSQKLNVSMADIIY 214
              |......|:.:.  |.| ::||.|.|:||||..|.:.||.:||..||.......|::.:|.|.
 Worm    96 NGKHVSRIAQNDENGLLAAESICYVIQTSGTTGAKKQVAVPVDCIRKNIEHFCSLFNLTSSDSIL 160

  Fly   215 LGTPITFDPFVVEFFLALQNGATLLTSRHSMRDSPSKVLSALFPDNLATPGITVLQMTPSLFRQF 279
            ..|.:.|||.:||.|:|...|.||:.:....|..|.|:..::  |....   ||:|:||::|...
 Worm   161 FSTSLHFDPSIVELFMAFHVGCTLIITPDEYRSEPHKLQKSI--DKFQP---TVVQLTPTVFEML 220

  Fly   280 GASSIKDRVLSGSSSLRVLLLGGEPFP-SNVELVTWMHPSVLMQKHICNIYGITEISCWSLLHIV 343
            .::   |.:||.:||||:|||||..|| |::....    |...:..:.|:||:||:|||:....|
 Worm   221 PSA---DSLLSATSSLRILLLGGSHFPISSINSCR----SPENKTRVFNVYGVTEVSCWASYFEV 278

  Fly   344 QSLQSPVPLGTPIEEDTVLRIESEDNETSQQGELFLGSVKRRCYIPEVDDQANASQDDSGICFRA 408
            :...|.|.:|..| ..|.|.::|:       |:|.||. .|:||:    |...|..       ..
 Worm   279 EHGCSEVLIGEAI-YGTQLGVDSD-------GQLILGG-PRQCYV----DGVKALN-------HK 323

  Fly   409 TGDLVTRQQDGTLFYSERSNDVVKRAGNRISLGLITRKIQKCLPSSELTTCLWLEDLQKLICCIR 473
            |||.|...::|......|.:.::|..|.||.|..::....:..||        ::.|..::
 Worm   324 TGDRVEVTENGGQKIVGRIDRLIKHRGIRICLDHLSHVALRHDPS--------IQSLHTML---- 376

  Fly   474 TLESKTRVQQRV------QTFDILSKVSIAEQPDRFVYLQHFPCNVHGKLDKQQLLKMCIPLAQP 532
             |:::..||..|      .|...|...:....|...:.:...|.|..||:|::.|.::...::..
 Worm   377 -LDNRNIVQFHVGPGSSSPTHKTLRLDATTVVPITVIQVAELPINSSGKVDEKALERIYGKVSGG 440

  Fly   533 AQQILKSYLHDRLECVEEPDDSASKKQRLDDAAPCGYDLSFRQAGGTSFHAITICREIGLQMCID 597
            .....:.....:|            |.:|.:.    .|:||...|..|..|..:.....:
 Worm   441 GNSKFQEIFEQKL------------KVKLSEV----LDVSFVSLGVNSLLAAELSTFFQV----- 484

  Fly   598 DEQRHLFEMLLDENIPLRTVLRFLDTAKLVANNIKRKNVETAVVVSACQSGLIIKRIEQPVLKLQ 662
            .:|..:...:|:|.:|:..|||..:.:..:.:::   :.|...::          |..||.::
 Worm   485 SQQTEVMRRMLNETVPVGDVLRKFELSPKLQSHV---DFEVRKII----------RKRQPKMR-- 534

  Fly   663 IYWKVNFEKCIDSPVTEYEGRFICVGAHSKILRTLNPQTGSEYSVVKLPERIECKVTFLTEQLAM 727
              |.|:..||||..:.......:...:|:.|:..:|||||:.....:...|.|||...:.:|: :
 Worm   535 --WAVDLRKCIDGNLLVICNTLVVCASHAGIVIAVNPQTGNLIWRAECGVRFECKPILVNDQV-V 596

  Fly   728 VGCYDGCLYGFNPQTG---NIVFRVGIGGLIKSQPMLTADGRRIIVCSYADDYNVYCLSAERQEV 789
            :||....||....:||   |.|....:|  :::|  ...|| ..|.|: .::.|.:.:..:....
 Worm   597 LGCKSTGLYFICVKTGQIQNSVILETVG--VRAQ--CAFDG-GAIYCT-TENGNFHVIDPKTYGS 655

  Fly   790 LWCLRIGEKP--IFASPLELPREQSLIVCTLDGSYSRVAITDGSVEWTQK--------------- 837
            ::...|.:.|  ....|:..|          |||.. ..||.|:|..|.|
 Worm   656 IYSHAISKIPGGTSVGPVIAP----------DGSIF-ATITAGAVLRTTKNPYSSTEFGAATRFG 709

  Fly   838 --FREPVF-STPVLLESVSNIFLSAEVAGRVHACHVGNGKILATFSTEG-NIF--------SSLV 890
              |.||:| .:.|::.:|..:..|.:|.         :|:.....|.|. |.|        |.|:
 Worm   710 PIFAEPLFVGSSVIITTVHGVLTSFDVE---------SGRRQDQISLENENCFCAPLPIANSHLL 765

  Fly   891 VKTPPTFMGHSFAIFGCIDQHLYCLRCKTGPGGKSVELELHWKVDV-----------GAPIYATP 944
            |.|                           ..|..:.:.|..|:.:           |.....||
 Worm   766 VAT---------------------------QSGTVLHVSLSPKLSILSIFRFDLPSPGISYVKTP 803

  Fly   945 TLL-----TVQPNGLLVWCAATDGRVML--INFRNGEIQWSDKLP---GQVFSSACFIEDLRR-- 997
            ..|     ..:|   ::...:..|.::|  |:...||:|..:.:|   .::|:|...|:::.|
 Worm   804 KFLRRSCGDKKP---MIMMTSKSGWLILAEISENGGELQNLEAIPISNKEIFTSPEIIDNVGRGG 865

  Fly   998 -----VFVGCRDNFL 1007
                 :.:..||::|
 Worm   866 AGNNILLIAGRDDYL 880

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aasdh	NP_609230.2	AA-adenyl-dom	46..443	CDD:273779	109/358 (30%)
		AFD_class_I	<168..522	CDD:302604	107/361 (30%)
		PQQ_DH_like	<728..1012	CDD:299747	67/340 (20%)
		PQQ_2	732..978	CDD:290097	57/295 (19%)
W09D6.1	NP_001255106.1	A_NRPS_acs4	4..430	CDD:341309	124/443 (28%)
		PP-binding	443..505	CDD:376348	13/82 (16%)
		PQQ_2	535..742	CDD:379140	55/233 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167223
Domainoid	1	1.000	119	1.000	Domainoid score	I3633
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I2911
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D424682at33208
OrthoFinder	1	1.000	-	-		FOG0002418
OrthoInspector	1	1.000	-	-		oto17318
orthoMCL	1	0.900	-	-		OOG6_100454
Panther	1	1.100	-	-	LDO	PTHR44394
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5888
SonicParanoid	1	1.000	-	-		X5394
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.930