Protein Alignment D12 and mllt1a

DIOPT Version :10

• Sequence 1: NP_609228.2
• Gene: D12 / 34172
• FlyBaseID: FBgn0027490
• Length: 969
• Species: Drosophila melanogaster
• Sequence 2: XP_009302187.1
• Gene: mllt1a / 565484
• ZFINID: ZDB-GENE-081105-45
• Length: 582
• Species: Danio rerio
• Alignment Length: 537
• Identity: 96/537 - (17%)
• Similarity: 168/537 - (31%)
• Gaps: 232/537 - (43%)

  Fly   275 TYKWLVYVQGKDLPE--PLEKYIKKVRFHLHPSY-RPNDIVDVHRSP-FQLNRHGWGEFPMRIQL 335
            |:.|:|:|:|   ||  .::.::.||.|.||.|: :|..:.   :.| :::...|:..|.|.|::
Zfish    29 THDWMVFVRG---PEGSDIQHFVDKVVFRLHESFPKPKRVC---KEPQYKVEESGYAGFLMPIEV 87

  Fly   336 FFQEHLQQKPVQLMHTVVL--------DKTMC--------------------GLHTM--GAET-- 368
            :|:...:.|.|...:.:.|        :...|                    ||..:  |||.
Zfish    88 YFKNKEEPKKVCFNYDLFLNLEGNPPVNHLRCEKLTFNNPTRDFRRKLVKAGGLIVVPEGAEVVP 152

  Fly   369 ----------TVEIWLRAKQAITKQKSGKPHPPHEQETAVPAPPLAAPNVLEP-----SVFAFPG 418
                      |:.:...:....:|...|...|..|......:..:|..:...|     |.....|
Zfish   153 RPSPDYPMLPTIPLSAFSDPKKSKTSQGSKEPSKEGSKVSKSHKMAKEHRERPRKDSESKATSKG 217

  Fly   419 ESCK---------PRTISITQNKEELDDNLFAGINKIELSDDIEKIEPTVLVSEP-LKLNYS--- 470
            :|.:         |.:.|.:.:|:          .:|::.|| .|:.|.....|| |.|..|
Zfish   218 DSERDGTSKSSRDPSSSSSSSSKK----------TEIKVKDD-NKVLPKAAFKEPKLTLKESKME 271

  Fly   471 -----------------------PRKQPPTPSSP---------------------------PRTQ 485
                                   |.|:|....||                           |||.
Zfish   272 SMSPKGGGAGAAGGGGGAADGKAPSKRPSNAESPKPSVKKPKKGSSEGSKCSGSGGFTGTSPRTT 336

  Fly   486 LRLNAAQVTA------------------------------------------SKPSVVYLPVNGR 508
            ...|.:...|                                          |:.|....|.|..
Zfish   337 SSSNTSSGYAEKKTSKEKGRWAKGKSEAQGVKETKKPPESDDSNSDDEASSKSEQSAPSSPSNSS 401

  Fly   509 SPRQESL-----PERQR------------------------QEFSPVKHYPPASPQRAWKESSSD 544
            |..:.|.     ||:::                        .|.:|||:..|:...|...:|.||
Zfish   402 SSSESSSDSDFEPEQKQGQGPLRSMVEDLQSEESDDDDSSSDEETPVKNNLPSRDSRLSLDSESD 466

  Fly   545 ------RP-------PIKPVPNGHHQGKKN---------VV---FQRAGKLY---IIDPLQRKLK 581
                  ||       |.|...|....|:|:         |:   :.:.|:.|   ::| |.|:|
Zfish   467 CSDGPQRPSRDAPPQPPKHSSNNKVSGRKSPDPCLRQEKVLKKGYDKVGRAYTDELVD-LHRRL- 529

  Fly   582 QAAKQQSLLKPQLSLLK 598
            .|.:::::|:..::|::
Zfish   530 MALRERNVLQQIVNLIE 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
D12	NP_609228.2	YEATS_YEATS2_like	249..375	CDD:341126	30/145 (21%)
mllt1a	XP_009302187.1	YEATS_AF-9_like	9..137	CDD:341125	24/113 (21%)
		AHD	518..578	CDD:436050	8/31 (26%)