DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment D12 and Mllt1

DIOPT Version :9

Sequence 1:	NP_609228.2	Gene:	D12 / 34172	FlyBaseID:	FBgn0027490	Length:	969	Species:	Drosophila melanogaster
Sequence 2:	NP_001100346.1	Gene:	Mllt1 / 301119	RGDID:	1588581	Length:	547	Species:	Rattus norvegicus

Alignment Length:	297	Identity:	61/297 - (20%)
Similarity:	113/297 - (38%)	Gaps:	60/297 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   275 TYKWLVYVQGKDLPE--PLEKYIKKVRFHLHPSY-RPNDIVDVHRSPFQLNRHGWGEFPMRIQLF 336
            |:.|:|:|:|   ||  .::.:::||.|.||.|: :|..:  ....|:::...|:..|.|.|:::
  Rat    29 THDWMVFVRG---PEQCDIQHFVEKVIFRLHDSFPKPKRV--CKEPPYKVEESGYAGFIMLIEVY 88

  Fly   337 FQEHLQQKPVQLMHTVVL--------DKTMCGLHTMGAETTVEIWLRAKQAIT---------KQK 384
            |:...:.:.|...:.:.|        :...|...|....||.   .|.|..:.         ...
  Rat    89 FKNKEEPRKVCFTYDLFLNLEGNPPVNHLRCEKLTFNNPTTE---FRCKLLMAGGVMVMPEGADT 150

  Fly   385 SGKPHPPHEQETAVPAPPLAAPNVLEPS-----VFAFPGESCKPRTISITQNKEELDDNLFAGIN 444
            ..:|.|.:.....:|....:.|...:||     .....|::.||..::....:....|:.....:
  Rat   151 VSRPSPDYPMLPTIPLSAFSDPKKNKPSHGSKDANKESGKASKPHKVAREHRERPRKDSESRSCS 215

  Fly   445 K------IELSDDIEKI--------------EPTVLVSEPLKLNYSPR--KQPPT-PSSPPRTQL 486
            |      ....|...|:              ||.:.:.|....:.||:  .|||| |.:..:...
  Rat   216 KEPEREPKSAKDAARKLPKEEKAPVPKAAFKEPKMALKETKLESLSPKGVSQPPTLPKASSKRPA 280

  Fly   487 RLNAAQVTASKP----SVVYLPVNGRSPRQESLPERQ 519
            ..::.:.:|.||    |.......|.|||..|.|:::
  Rat   281 ATDSPKPSAKKPKKSGSKGARRAPGTSPRASSFPDKK 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
D12	NP_609228.2	YEATS	275..357	CDD:281374	22/92 (24%)
Mllt1	NP_001100346.1	YEATS_AF-9_like	9..137	CDD:341125	28/115 (24%)
		PRK10905	<218..>351	CDD:236792	22/100 (22%)
		AHD	483..543	CDD:407665
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5033
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810