Protein Alignment D12 and yeats2

DIOPT Version :10

• Sequence 1: NP_609228.2
• Gene: D12 / 34172
• FlyBaseID: FBgn0027490
• Length: 969
• Species: Drosophila melanogaster
• Sequence 2: XP_012825478.1
• Gene: yeats2 / 100135359
• XenbaseID: XB-GENE-5865259
• Length: 1238
• Species: Xenopus tropicalis
• Alignment Length: 1353
• Identity: 260/1353 - (19%)
• Similarity: 445/1353 - (32%)
• Gaps: 519/1353 - (38%)

  Fly    12 RRHSEYHDPDYQQTEVSSQDEEETCAEAESPGQRKWTKTEQSDGMLPLSDKFQRIRELLRLEFQR 76
            :|.||..||||:...|..|::....||           |...|..:      .:|..:::.:|..
 Frog     5 KRSSEDKDPDYEDISVVHQNKRHKAAE-----------TTARDATI------LKIESIIKEQFVT 52

  Fly    77 EISQKVEQLAEIDRRLLQGRQLLDRLRYQVVSEYY-----RKQQVPLTGADIAKVRGDSLFGDDI 136
            |:..|..::..||:||.:.|:::|:||..:|:.||     .|.|           .|.|.:...:
 Frog    53 ELKNKEHEVEVIDQRLNEARRMMDKLRACIVANYYASAALNKNQ-----------EGPSSYDATV 106

  Fly   137 AAPQLPLHPAIKKIVGKRPVVIQNHLPERTAATLAKETIRLRNPAHRRAERRRQQKIKEQGIVTD 201
            ..     ||:|||.:         ..|.|.:           :||::|:|.......:...:.|
 Frog   107 LN-----HPSIKKFL---------ESPSRAS-----------SPANQRSETPSVANSETDSVYT- 145

  Fly   202 HSKDKKDQPEQEPPISVK-LEDE-----QPCTSRQAHERQVELNASRLNNKNKFNFVVGNTSKYI 260
            |::||....:.:.|.:.| |..|     .|..:... ||||...........|...||||.||||
 Frog   146 HNEDKDGSLDAKGPAANKALRPEGNTVKDPSINENT-ERQVSRTEDGPRRFVKKTIVVGNVSKYI 209

  Fly   261 GEDSRENGTGGNALTYKWLVYVQGKDLPEPLEKYIKKVRFHLHPSYRPNDIVDVHRSPFQLNRHG 325
            ..|.||.   .:..|:||:|||:|......::.::|||.|.|||||:|||:|:|...||.|.|.|
 Frog   210 PPDKREE---NDQSTHKWMVYVRGSRKEPSIDHFVKKVWFFLHPSYKPNDLVEVSEPPFHLTRRG 271

  Fly   326 WGEFPMRIQLFFQEHLQQKPVQLMHTVVLDKTMCGLHTMGAETTVEI----------WLRAKQA- 379
            |||||:|:|:.|::. |.|.:.::|.:.||:|..||.|:||||.||:          :|.::.:
 Frog   272 WGEFPVRVQIHFKDS-QNKRIDIIHNLKLDRTYTGLQTLGAETVVEVEIYRHSLGEDFLGSQSSN 335

  Fly   380 ---------ITKQKSGKPHP-PHE----QETAVPAP-------------------------PLAA 405
                     ::..||..||. .||    :.:..|.|                         |:.|
 Frog   336 ECAQSEASLLSHVKSSSPHKVAHESADKEPSYYPQPSSLERTPTKVAQRLSFGIPGSTAFQPITA 400

  Fly   406 PNVLEP-----SVFAFPGESCKPRTI-----------------------------------SITQ 430
            ...:.|     |:...||:|.:|.|:                                   |.|.
 Frog   401 SCKIVPQGQAASLAESPGKSFQPITMSCKIVSGTGSPTSKHSSTSQGASGTKSPVPKLHGTSFTP 465

  Fly   431 NKEELDDNLFAG-----------------------------INKIELSDDIEKIEPTVLVSEP-- 464
            ...:.:|::||.                             |.|.|.::..::::.....|:|
 Frog   466 QNIKQEDSMFAAMPPLCPIGSQPKAQSPKTVTGGLGAFTKVIIKQEPTEPTQQLQEAPSTSQPPL 530

  Fly   465 -----LKLNY----SPRKQPPT--------------------PS--------------------- 479
                 :|.|:    ||:|...|                    ||
 Frog   531 QQIVTVKGNHMVAVSPQKNLATSEGSKVVGIPVGTTVQAAIKPSVTISGGQILVAKSSSSIAKAV 595

  Fly   480 ----------------------------SPPRTQLRLNAAQVTASKPSV---------------- 500
                                        |..:.|:....||...|:.||
 Frog   596 GSKQIVAQGVAKAVVSSGSGNVVAQSSQSVSKAQVTSAVAQKAGSQGSVMATLQLPASNIPNLAN 660

  Fly   501 ------VYLPVNGRSP-------------------------------------RQESLPERQRQE 522
                  :||..|.::|                                     ....||:.....
 Frog   661 LPPGTKLYLTTNSKNPSGKGKLLLIPQGAILRAANTASLQSGASSSGGSSTASTTSGLPQHLTYT 725

  Fly   523 FSPVKHYPPA-------SPQRAWKESSSD---RPPIKPVPNGHH--------------------- 556
            ...:|..|..       |.|.:.|:::::   :..:.....||.
 Frog   726 SYILKQTPQGTFLVGQQSQQASGKQAAANVIVQGNVATSAQGHQTLKLTTGPKGTLVAQTHSASA 790

  Fly   557 ---------------QGKK-------------------------NVVFQRAGKLYIIDPLQRKLK 581
                           |.:|                         ||..|:|..:......|....
 Frog   791 AVAKISDGAVTSVQSQTQKPGTTLLRVAGGVITASSASLPSVSTNVSTQQAADVSSTSTTQVSAS 855

  Fly   582 QAAKQQSLLK-----PQLSLLKPP------SETRWHMLQCMQHDHGYANM--------------- 620
            ..:..|.::.     ..|..:||.      |.||...............|
 Frog   856 NKSISQQVMARIAHVKSLGTVKPATSAAAVSSTRTAPTLAQSSAASAVKMEPDMTSNASSTSGPG 920

  Fly   621 ---------SGEMEEKPMLLPPIVD-TTIQSRPRRLEHIFRSAQFRNMRSAVEFLLSRLPLASID 675
                     |||.:...:.:...|: .::::|....||:      :|.:..:..::.::||.:..
 Frog   921 SSTPVKTEESGESDPSSVRVVGQVECASLRARHNWTEHL------QNFKQLLTAIVKKVPLLAEK 979

  Fly   676 QQKEYPFTCITLEEFHNHTALKQRCFEYLRARMLRRCLMQHHELHKLDISGKEHYWS------LR 734
            .:....|...::|::::....|:|..|:.||..:::.|.        :|..|:..:|      .:
 Frog   980 SEDGNAFCATSVEQYYSWNIGKRRASEWQRAVTMKKMLQ--------EIIEKQPKFSNVAPLKTK 1036

  Fly   735 EIVAFARVHGYTPALKDVLPVVHEKRKQKLSDEEQLARRVQAQLKGEP--QPQLSAYSSL-SSGN 796
            :||.:.|:|||||...:.|.          ||:|.: ..|.|::..|.  |...||...| ....
 Frog  1037 QIVHWCRIHGYTPPDPESLG----------SDKESI-EDVLARIDNEAALQTSFSAPDILCQKME 1090

  Fly   797 RLEAWITKQSDRLLGHDQQMRDKEFIDVLGVDKPHPLASRLTNSA--DVSFQMVNHRQLLYLPPP 859
            .||....|:::         .|.: :|||..::...|..:..:.|  |....||.
 Frog  1091 ELEKTFKKETE---------EDVD-VDVLSANEEQRLHIKKESEAEEDAKLYMVT---------- 1135

  Fly   860 KHLDSTLQLVQEMCKDINITLEPEESPPGVSQPLALSMLGQVLRTFIEKLVRRSLAAKLQ----- 919
               ....:.:::..::|.::::|.|....:.......|:.:....|:..::|.:|....|
 Frog  1136 ---SPACEFIRDKAQEIGVSVQPVEVQDNIYTSAVEEMILKATEQFVSDVLRDALGVAYQMTSHN 1197

  Fly   920 ---QE-TLEQLPPAAANAPLCLQPQDIGRVISLCSELDFLGNSHLGVAPIEPQ 968
               || |:..:..|..|.|:                .|||.|.|:..:..|.:
 Frog  1198 RAPQEITVSNIHQAICNIPM----------------FDFLTNKHMASSTTEDE 1234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
D12	NP_609228.2	YEATS_YEATS2_like	249..375	CDD:341126	60/135 (44%)
yeats2	XP_012825478.1	YEATS_YEATS2_like	198..321	CDD:341126	60/126 (48%)