Protein Alignment IDH1 and Idh1

DIOPT Version :10

• Sequence 1: NP_005887.2
• Gene: IDH1 / 3417
• HGNCID: 5382
• Length: 414
• Species: Homo sapiens
• Sequence 2: NP_034627.3
• Gene: Idh1 / 15926
• MGIID: 96413
• Length: 414
• Species: Mus musculus
• Alignment Length: 414
• Identity: 396/414 - (95%)
• Similarity: 406/414 - (98%)
• Gaps: 0/414 - (0%)

Human     1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIK 65
            ||:||.|||||||||||||||||||||||||.|||||||||||||||||||||||||||||||||
Mouse     1 MSRKIQGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDAAEAIK 65

Human    66 KHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIII 130
            |:||||||||||||||||||||||||||||||||||||||||||||||||||||||:||||||||
Mouse    66 KYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWVKPIII 130

Human   131 GRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHS 195
            ||||||||||||||||||||||||||||.||||||||:||:||||||||||||||||||||||||
Mouse   131 GRHAYGDQYRATDFVVPGPGKVEITYTPKDGTQKVTYMVHDFEEGGGVAMGMYNQDKSIEDFAHS 195

Human   196 SFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMK 260
            ||||||||||||||||||||||||||||||||||||||:||||||||||.|||||||||||||||
Mouse   196 SFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFEAQKICYEHRLIDDMVAQAMK 260

Human   261 SEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQET 325
            |||||||||||||||||||||||||||||||||||:|||||||||||||||||||||||||||||
Mouse   261 SEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHGTVTRHYRMYQKGQET 325

Human   326 STNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSD 390
            |||||||||||:||||||||||||.||:|||.|||:|.|||||||||||||||||||||||||||
Mouse   326 STNPIASIFAWSRGLAHRAKLDNNTELSFFAKALEDVCIETIEAGFMTKDLAACIKGLPNVQRSD 390

Human   391 YLNTFEFMDKLGENLKIKLAQAKL 414
            ||||||||||||||||.|||||||
Mouse   391 YLNTFEFMDKLGENLKAKLAQAKL 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IDH1	NP_005887.2	PTZ00435	1..411	CDD:240417	391/409 (96%)
Idh1	NP_034627.3	PTZ00435	1..411	CDD:240417	391/409 (96%)