DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG13398 and DOK5

DIOPT Version :9

Sequence 1:NP_001260252.1 Gene:CG13398 / 34169 FlyBaseID:FBgn0032042 Length:442 Species:Drosophila melanogaster
Sequence 2:NP_060901.2 Gene:DOK5 / 55816 HGNCID:16173 Length:306 Species:Homo sapiens


Alignment Length:197 Identity:51/197 - (25%)
Similarity:83/197 - (42%) Gaps:31/197 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MGCITSSSKLNELR-GHENVFRVRV---------AHLQPTPGTPIIRSGYLELTPRELIF---QS 52
            |.|:  .:::|::. |..::....|         .:|.|:|...:.....|::|...:..   |:
Human   109 MECV--GTRINDISLGEPDLLATGVEREQSERFNVYLMPSPNLDVHGECALQITYEYICLWDVQN 171

  Fly    53 PGCEPIVWALQHLRRYGLNNDLFSFEAGRRCMSGPGIYTFRVHNAEQLYPMFQRYINAVNTDAFV 117
            |..:.|.|.|..|||||.:...|:|||||.|.:|.|::.|:..:.|.:|       ..|::.|..
Human   172 PRVKLISWPLSALRRYGRDTTWFTFEAGRMCETGEGLFIFQTRDGEAIY-------QKVHSAALA 229

  Fly   118 QGER-ER-VNSAHSVSVNMGRTEGNNYLEP-APLMSRQLGNFHSEPSSTSASYPLQANDSQVDDS 179
            ..|: || :.|..:..:.|..:|....|.. .||.........:...||...|.||      |.|
Human   230 IAEQHERLLQSVKNSMLQMKMSERAASLSTMVPLPRSAYWQHITRQHSTGQLYRLQ------DVS 288

  Fly   180 PP 181
            .|
Human   289 SP 290

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG13398NP_001260252.1 PTB_FRS2 15..109 CDD:269913 29/105 (28%)
DOK5NP_060901.2 PH_DOK4_DOK5_DOK6 9..113 CDD:270197 2/5 (40%)
PTB_DOK4_DOK5_DOK6 133..235 CDD:241318 30/108 (28%)
DKFBH motif 263..273 1/9 (11%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165141608
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4047
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.830

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