DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13398 and Dok4

DIOPT Version :9

Sequence 1:	NP_001260252.1	Gene:	CG13398 / 34169	FlyBaseID:	FBgn0032042	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	NP_001101908.1	Gene:	Dok4 / 361364	RGDID:	1310084	Length:	325	Species:	Rattus norvegicus

Alignment Length:	243	Identity:	61/243 - (25%)
Similarity:	93/243 - (38%)	Gaps:	56/243 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 CITSSSKLNELRGHE----------------NVFRVRVAHLQPTPGTPIIRSGYLELTPRELI-- 49
            |:  .|:||::...|                |||      |.|.|...:.....|::|...:.
  Rat   111 CL--GSRLNDISLGEPDLLAPGVQCEQTDRFNVF------LLPCPNLDVYGECKLQITHENIYLW 167

  Fly    50 -FQSPGCEPIVWALQHLRRYGLNNDLFSFEAGRRCMSGPGIYTFRVHNAEQLYPMFQRYINAVNT 113
             ..:|..:.:.|.|..|||||.:...|:|||||.|.:|.|:|||:....||:|   || :::...
  Rat   168 DIHNPRVKLVSWPLCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQTQEGEQIY---QR-VHSATL 228

  Fly   114 DAFVQGERERVNSAHSVSVNMGRTEGNNY-LEPAPLMSRQLGNFH-------SEPSSTSASYPLQ 170
            ....|.:|..:....:|.:....||..:| ..|..::.|.....|       :|.||....|...
  Rat   229 AIAEQHKRVLLEMEKNVRLLNKGTEHYSYPCTPTAMLPRSAYWHHITGSQNIAEASSYGEGYGAA 293

  Fly   171 ANDSQVDDSPPNLQSPVLIPSAYLDQPLRALQDCCLEGTASDLLSTPP 218
            ...|:.|          |:....|.:|....:|       |....|||
  Rat   294 QASSETD----------LLNRFILLKPKPRQED-------SSETKTPP 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13398	NP_001260252.1	PTB_FRS2	15..109	CDD:269913	34/112 (30%)
Dok4	NP_001101908.1	PH	8..108	CDD:278594
		PH_DOK4_DOK5_DOK6	9..113	CDD:270197	1/3 (33%)
		PTB_DOK4_DOK5_DOK6	133..235	CDD:241318	34/111 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335302
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4047
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.830