DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13398 and Dok3

DIOPT Version :9

Sequence 1:	NP_001260252.1	Gene:	CG13398 / 34169	FlyBaseID:	FBgn0032042	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	XP_038951545.1	Gene:	Dok3 / 306760	RGDID:	1311840	Length:	481	Species:	Rattus norvegicus

Alignment Length:	243	Identity:	66/243 - (27%)
Similarity:	95/243 - (39%)	Gaps:	62/243 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 WALQHLRRYGLNNDLFSFEAGRRCMSGPGIYTFRVHNAEQLYPMFQRYINAVNTDAFVQGERERV 124
            |..:.||::|.:..:|||||||||.||.|::.|....|..:       ..||  .|.:..:|||:
  Rat   240 WPYRFLRKFGSDKGVFSFEAGRRCDSGEGLFAFSSPRAPDI-------CGAV--AAAIARQRERL 295

  Fly   125 -NSAHSVSVNMGRTEGNNYLEPAPLMSRQLGNFHSEPSSTSASYPLQANDSQVDDSPPNLQSPVL 188
             ..|.|....:.|......|||...:......:...|   |...||      .|..|.:|  |:|
  Rat   296 PELAMSPPCPLPRALSLPSLEPPGELREVAPEYELAP---SRKLPL------TDPGPQSL--PLL 349

  Fly   189 IPSAYLDQPLRALQDCCLEGTASDLLST---PPSGNRLTSRRRTMDLPPLESAP----------- 239
                     |...||    ||||.|.::   ..|.::.|......::..||::|
  Rat   350 ---------LSPTQD----GTASSLYASVCKQTSKHKATVEHLYENVFMLEASPGLSNGGPEAQE 401

  Fly   240 ----APAPVLSPNDAVHMYANVEALIF-----DLNNERCYENVNRLEL 278
                ..:|:.||     :|.|.|.|.:     |.|.|..|..:..|||
  Rat   402 GPPGGRSPLGSP-----IYHNSEELSWPGSAHDSNLEAQYRRLLELEL 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13398	NP_001260252.1	PTB_FRS2	15..109	CDD:269913	18/48 (38%)
Dok3	XP_038951545.1	PH-like	46..160	CDD:418428
Dok3	XP_038951545.1	PTB_DOK1_DOK2_DOK3	194..292	CDD:269914	21/60 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335300
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4047
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.790