DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13398 and Dok2

DIOPT Version :9

Sequence 1:	NP_001260252.1	Gene:	CG13398 / 34169	FlyBaseID:	FBgn0032042	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	XP_038949088.1	Gene:	Dok2 / 290361	RGDID:	1310966	Length:	429	Species:	Rattus norvegicus

Alignment Length:	247	Identity:	60/247 - (24%)
Similarity:	91/247 - (36%)	Gaps:	66/247 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 TSSSKLNELRGHENVFRVRVAHLQ----PTPGTPIIRSGYLELTPRELIFQSPGCEPIVWALQHL 65
            |.:|:...||| ....|..|:.|:    |.|||.:..                      |..:.|
  Rat   177 TEASERCRLRG-SYTLRTGVSALELWGGPEPGTQLYD----------------------WPYRFL 218

  Fly    66 RRYGLNNDLFSFEAGRRCMSGPGIYTFRVHNAEQLYPMFQRYINAVNTDAFVQGERERVNSAHSV 130
            ||:|.:...|||||||||:||.|.:.|......:::...::.| |...:|...|......:...:
  Rat   219 RRFGRDKVTFSFEAGRRCVSGEGSFEFETRQGNEIFQALEKAI-AAQKNATPSGPPTLPATGSMM 282

  Fly   131 SVNMGRTEGNNYLEP----------APLMSRQLGNFHSE---PSSTSASYPLQANDSQVDDSPPN 182
            ...:.|.| :.|..|          .|:...:.|....|   |..| ..:.|:.:...:...||.
  Rat   283 PTALPRPE-SPYSRPHDSLPSPSPGTPVPGIRSGGSEGEYAVPFDT-VVHSLKKSFRGILTGPPP 345

  Fly   183 L----------QSPVL-IPSAYLDQPLRALQDCCLEGTASDLL---STPPSG 220
            |          :.||: :|....|:|         ||.|:..|   |..|||
  Rat   346 LLPDPLYDSIQEDPVVPLPDHIYDEP---------EGVAALSLYERSQKPSG 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13398	NP_001260252.1	PTB_FRS2	15..109	CDD:269913	26/97 (27%)
Dok2	XP_038949088.1	PH-like	42..134	CDD:418428
Dok2	XP_038949088.1	PTB_DOK1_DOK2_DOK3	167..265	CDD:269914	32/111 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335304
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4047
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.790