DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13398 and Dok3

DIOPT Version :9

Sequence 1:	NP_001260252.1	Gene:	CG13398 / 34169	FlyBaseID:	FBgn0032042	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	NP_038767.1	Gene:	Dok3 / 27261	MGIID:	1351490	Length:	444	Species:	Mus musculus

Alignment Length:	238	Identity:	66/238 - (27%)
Similarity:	91/238 - (38%)	Gaps:	52/238 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 WALQHLRRYGLNNDLFSFEAGRRCMSGPGIYTFRVHNAEQLYPMFQRYINAVNTDAFVQGERERV 124
            |..:.||:||.:..:|||||||||.||.|::.|....|..:..:         ..|.:..:|||:
Mouse   203 WPYRFLRKYGSDKGVFSFEAGRRCDSGEGLFAFSSPRAPDICGV---------VAAAIARQRERL 258

  Fly   125 -NSAHSVSVNMGRTEGNNYLEPAPLMSRQLGNFHSEPSSTSASYPLQANDSQVDDSPPNLQSPVL 188
             ..|.|....:.|......||| |...|::......|  |....||         :.|..||..|
Mouse   259 PELAMSPPCPLPRALSLPSLEP-PGELREVAPGFELP--TPRKLPL---------TDPGPQSLPL 311

  Fly   189 IPSAYLDQPLRAL-QDCCLE-----GTASDL------LSTPPSGNRLTS-RRRTMDLPPLESAPA 240
            :.|...:.|...| ...|.:     |||..|      |...|.   ||: .....:.||...:|.
Mouse   312 LLSPTQEGPASGLYASVCKQTSKHTGTAEHLYENVCMLEASPG---LTNGGPEAQEGPPGGRSPL 373

  Fly   241 PAPVLSPNDAVHMYANVEALIF-----DLNNERCYENVNRLEL 278
            .:|:         |.|.|.|.:     |.|.|..|..:..|||
Mouse   374 GSPI---------YHNTEDLSWPGSAQDSNLEAQYRRLLELEL 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13398	NP_001260252.1	PTB_FRS2	15..109	CDD:269913	19/48 (40%)
Dok3	NP_038767.1	PH_DOK1,2,3	9..123	CDD:270195
		PTB_DOK1_DOK2_DOK3	157..255	CDD:269914	20/60 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	278..299		7/23 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	354..390		10/47 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831557
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4047
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.790