Protein Alignment CG13398 and FRS3

DIOPT Version :9

• Sequence 1: NP_001260252.1
• Gene: CG13398 / 34169
• FlyBaseID: FBgn0032042
• Length: 442
• Species: Drosophila melanogaster
• Sequence 2: NP_006644.1
• Gene: FRS3 / 10817
• HGNCID: 16970
• Length: 492
• Species: Homo sapiens
• Alignment Length: 507
• Identity: 124/507 - (24%)
• Similarity: 171/507 - (33%)
• Gaps: 175/507 - (34%)

  Fly    38 SGYLELTPRELIFQSPGCEPIVWALQHLRRYGLNNDLFSFEAGRRCMSGPGIYTFRVHNAEQLYP 102
            ||.:|||..||:......|.:.|....|||||.:::|||||:||||.:|.||:.|:...||:::.
Human    35 SGVMELTQSELVLHLHRREAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFN 99

  Fly   103 MFQ-----RYINAVNTDAFVQGERERVNSAHSVSVNMGRTEGNNYLEPAPLMSRQLGNFHSEPSS 162
            :.|     ..||.:.....:      ..::|...:::.|         ||.....||
Human   100 LLQDLMQCNSINVMEEPVII------TRNSHPAELDLPR---------APQPPNALG-------- 141

  Fly   163 TSASYPLQANDSQVDDSPPNLQSPVLIPSAYLDQPLRALQDCCLEGT----ASD-----LLSTPP 218
                |.:.:..:......|...:|..:.::.|..|  :|.:   |.|    |.|     .::||.
Human   142 ----YTVSSFSNGCPGEGPRFSAPRRLSTSSLRHP--SLGE---ESTHALIAPDEQSHTYVNTPA 197

  Fly   219 SGNRLTSRRRTMDLPPLESAPAP------AP----------------VLSPNDAVHMYANVEALI 261
            |.:  ..||....|.||....||      .|                ||.|..|.......:.|.
Human   198 SED--DHRRGRHCLQPLPEGQAPFLPQARGPDQRDPQVFLQPGQVKFVLGPTPARRHMVKCQGLC 260

  Fly   262 FDL--------NNE---------RC-YENVN---------RLELPLLPREP-------------- 285
            ..|        |||         :| ||||.         ||.    |.||
Human   261 PSLHDPPHHNNNNEAPSECPAQPKCTYENVTGGLWRGAGWRLS----PEEPGWNGLAHRRAALLH 321

  Fly   286 ISNQEPATPT------SLAGSCGVNYIVLDLDQPRSPVGPAGSSKAINGFGSG-------LSLIS 337
            ..|..|..|.      .|.|..|        |...|..|...||   |||..|       ....|
Human   322 YENLPPLPPVWESQAQQLGGEAG--------DDGDSRDGLTPSS---NGFPDGEEDETPLQKPTS 375

  Fly   338 TPAAVTA------PVTPEAGT----TLDV----PPPPMQTQSLNSISADT----GD--------- 375
            |.||:.:      |:|...|:    ..|.    |.||.|   ||.|..:.    ||
Human   376 TRAAIRSHGSFPVPLTRRRGSPRVFNFDFRRPGPEPPRQ---LNYIQVELKGWGGDRPKGPQNPS 437

  Fly   376 -TQAKKVT--ECSGTQGYSTIDFIRTYALNKSSTELPE---TVTHRQHSSHD 421
             .||...|  ....:..|:.||..:|.|::.....||.   |....:|:|.|
Human   438 SPQAPMPTTHPARSSDSYAVIDLKKTVAMSNLQRALPRDDGTARKTRHNSTD 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13398	NP_001260252.1	PTB_FRS2	15..109	CDD:269913	30/75 (40%)
FRS3	NP_006644.1	PTB_FRS2	15..106	CDD:269913	30/70 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	153..173		4/21 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	338..455		32/130 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	467..492		6/23 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141606
Domainoid	1	1.000	68	1.000	Domainoid score	I9723
eggNOG	1	0.900	-	-		E1_KOG4047
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D223604at33208
OrthoFinder	1	1.000	-	-		FOG0002576
OrthoInspector	1	1.000	-	-		otm41124
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR21258
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.940