| Sequence 1: | NP_001303316.1 | Gene: | emb / 34167 | FlyBaseID: | FBgn0020497 | Length: | 1063 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_003391.1 | Gene: | XPO1 / 7514 | HGNCID: | 12825 | Length: | 1071 | Species: | Homo sapiens |
| Alignment Length: | 1067 | Identity: | 756/1067 - (70%) |
|---|---|---|---|
| Similarity: | 885/1067 - (82%) | Gaps: | 8/1067 - (0%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 3 TMLTSDEAGKLLDFSQKLDINLLDKIVEVVYTAQGEQLRLAQSILTTLKEHPEAWTRVDSILEYS 67
Fly 68 QNQRTKFYALQILEEVIKTRWKVLPRNQCEGIKKYVVSLIIKTSSDPIVMEQNKVYLNKLNMILV 132
Fly 133 HILKREWPRNWETFISDIVGASKTNESLCMNNMVILKNLSEEVFDFSQGQITQTKAKHLKDTMCS 197
Fly 198 EFSQIFTLCSFVLENSMNAALIHVTLETLLRFLNWIPLGYIFETQQIETLIFKFLSVPMFRNVTL 262
Fly 263 KCLSEIAGLTAANYDENFATLFKDTMVQLEQIVGQNMNMNHVFKHGSDTEQELVLNLAMFLCTFL 327
Fly 328 KEHGKLVEDAKYV-DYLNQALMYLVMISEVEDVEVFKICLEYWNSLVEDLYNSEFF----HPTLE 387
Fly 388 STKRQQVYPRRRFYAPILSKVRFIMISRMAKPEEVLVVENENGEVVREFMKDTNSINLYKNMRET 452
Fly 453 LVFLTHLDSVDTDRIMTLKLLNQVNGSEFSWKNLNTLCWAIGSISGAFCEEDEKRFLVTVIKDLL 517
Fly 518 GLCEQKKGKDNKAIIASNIMYVVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIK 582
Fly 583 IAIKCRRYFVTIQPNEACTFIDEILTTMSSIICDLQPQQVHTFYEAVGYMISAQVDQVQQDVLIE 647
Fly 648 RYMQLPNQVWDDIISRASKNVDFLKNMTAVKQLGSILKTNVAACKALGHAYVIQLGRIYLDMLNV 712
Fly 713 YKITSENIIQAIEVNGVNVNNQPLIKTMHVVKKETLNLISEWVSRSNDNQLVMDNFIPPLLDAIL 777
Fly 778 LDYQRCKVPSAREPKVLSAMAIIVHKLRQHITNEVPKIFDAVFECTLDMINKNFEDFPQHRLSFY 842
Fly 843 ELLQAVNAHCFKAFLNIPPAQFKLVFDSVVWAFKHTMRNVADMGLNILFKMLQNLDQHPGAAQSF 907
Fly 908 YQTYFTDILMQIFSVVTDTSHTAGLPNHAIILAYMFSLVENRKITVNLGP--IPDNMIFIQEYVA 970
Fly 971 SLLKSAFTHLSDNQVKVFVTGLFNLDENVQAFKEHLRDFLIQIREATGEDDSDLYLEEREAALAE 1035
Fly 1036 EQSNKHQMQRNIPGMLNPHELPEDMQD 1062 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| emb | NP_001303316.1 | CRM1 | 13..1023 | CDD:227432 | 729/1016 (72%) |
| IBN_N | 43..109 | CDD:197981 | 52/65 (80%) | ||
| Xpo1 | 120..265 | CDD:285575 | 114/144 (79%) | ||
| CRM1_C | 701..1015 | CDD:285920 | 223/315 (71%) | ||
| XPO1 | NP_003391.1 | Necessary for HTLV-1 Rex-mediated mRNA export | 1..679 | 484/672 (72%) | |
| CRM1 | 15..1044 | CDD:227432 | 739/1029 (72%) | ||
| Interaction with Ran and nuclear export complex formation | 327..450 | 69/122 (57%) | |||
| Interaction with RANBP3 | 411..481 | 57/69 (83%) | |||
| Necessary for HTLV-1 Rex multimerization | 411..414 | 1/2 (50%) | |||
| HEAT 7 | 775..813 | 29/38 (76%) | |||
| Interaction with HIV-1 Rev | 800..820 | 14/19 (74%) | |||
| HEAT 8 | 885..916 | 21/30 (70%) | |||
| HEAT 9 | 917..954 | 29/36 (81%) | |||
| HEAT 10 | 1002..1039 | 24/36 (67%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165145452 | |
| Domainoid | 1 | 1.000 | 446 | 1.000 | Domainoid score | I528 |
| eggNOG | 1 | 0.900 | - | - | E1_COG5101 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H2554 | |
| Inparanoid | 1 | 1.050 | 1510 | 1.000 | Inparanoid score | I100 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG53807 | |
| OrthoDB | 1 | 1.010 | - | - | D132850at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0003578 | |
| OrthoInspector | 1 | 1.000 | - | - | oto91089 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_101697 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR11223 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R13754 |
| SonicParanoid | 1 | 1.000 | - | - | X2450 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 16 | 15.800 | |||||